QuantiNova LNA PCR Focus Panel Human Toll-Like Receptor Signaling Pathway | GeneGlobe

Product Specification

Target List

Toll-Like Receptors

CD180SIGIRRTLR1TLR2TLR3TLR4TLR5TLR6TLR7TLR8TLR9TLR10

Pathogen-Specific Responses

Viral Response

EIF2AK2IFNB1IFNGIL12AIL6IRF3PRKRARELATBK1TLR3TLR7TLR8TNFTICAM1 (TRIF)

Fungal / Parasitic Response

CLEC4EHRASHSPA1A (HSP70-1A)CXCL8 (IL8)TLR2TIRAP

Toll-Like Receptor (TLR) Signaling

Negative Regulation of Toll-Like Receptor (TLR) Signaling

SARM1SIGIRRTOLLIP

TICAM1 (TRIF)-Dependent (MYD88-Independent) Signaling

IRF3MAP3K7 (TAK1)TAB1NR2C2 (TAK1)PELI1TBK1TICAM2 (TRAM)TLR3TLR4TRAF6TICAM1 (TRIF)

MYD88-Dependent Signaling

IRAK1IRAK2MAP3K7 (TAK1)TAB1MYD88NR2C2 (TAK1)TIRAPTLR1TLR10TLR2TLR4TLR5TLR6TLR7TLR8TLR9TRAF6

Signaling Downstream of Toll-Like Receptors

JNK / p38 Signaling

ELK1FOSIL1BJUNMAP2K3 (MEK3)MAP2K4 (MKK4, JNKK1)MAP3K1 (MEKK1)MAP3K7 (TAK1)MAPK8 (JNK1)MAPK8IP3TNF

JAK / STAT Signaling

CCL2 (MCP-1)CSF2 (GM-CSF)IFNGIL12AIL2IL6

Interferon Regulatory Factor (IRF) Signaling

CXCL10 (INP10)IFNA1IFNB1IFNGIRF1IRF3TBK1

Cytokine Signaling

CCL2 (MCP-1)CSF3 (GCSF)IL1AIL1BIL6IRAK1IRAK2RELASIGIRRTNFTNFRSF1A (TNFR1)

Regulation of Adaptive Immunity

CD80CD86HSPD1IFNGIL10IL12AIL1BIL2MAP3K7 (TAK1)TRAF6

Toll-Like Receptor Interacting Proteins & Adaptors

BTKCD14HMGB1HRASHSPA1A (HSP70-1A)HSPD1LY86 (MD-1)LY96 (MD-2)MAPK8IP3MYD88PELI1RIPK2SARM1TICAM1 (TRIF)TICAM2 (TRAM)TIRAPTOLLIP

Downstream Effectors of Toll-Like Receptor Signaling

CASP8 (FLICE)EIF2AK2FADDIRAK1IRAK2IRAK4MAP3K7 (TAK1)TAB1NR2C2 (TAK1)PPARAPRKRAECSITTRAF6UBE2N

Product Resources

Download Target List

Array Layout for PCR Plates

File Size: 153.16 KBLanguage: English

Array Layout for Rotor-Gene Q

File Size: 153.29 KBLanguage: English

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