Target List
Inflammasomes
NLRP1​
Negative Regulation of Inflammasomes​
NOD-Like Receptors
Signaling Downstream of NOD-Like Receptors​
Birc2 (cIAP1, cIAP2)Birc3 (cIAP1, cIAP2)Card6Casp8 (Flice)Ccl12 (MCP-5, Scya12)Ccl5 (Rantes)Ccl7 (mcp3)Cflar (Casper)Chuk (IKBKA)Cxcl3Cxcl1 (Gro1)FaddIfnb1Ikbkb (IKKbeta)IkbkgIl6Irf1Irf3Irf4Map3k7 (Tak1)Mapk1 (Erk2)Mapk11 (p38beta)Mapk12 (P38Gamma)Mapk13 (SAPK4, Serk4)Mapk3 (Erk1)Mapk8 (Jnk1)Mapk9 (Jnk2)Nfkb1Nfkbia (Iκbα, Mad3)Nfkbib (Trip9)Pea15aRelaRipk2Sugt1Tab1Tab2TirapTnfTraf6Xiap
Pro-Inflammatory Caspases