Target List
Covers specific hotspots of the targeted genes based on the Human GRCh38 genome build
Adenocarcinomas
ABL1, ALK, ATM, BRAF, CDK4, CDKN2A (P16INK4A), CTNNB1, EGFR (ERBB1), ERBB2 (HER-2, NEU), KRAS, MAP2K1, MET, NRAS, NTRK1, PIK3CA (p110-alpha), PTEN, RET, ROS1, TP53 (p53), TSC2
Malignant Pleural Mesotheliomas
NF2
Non-Small Cell Lung Cancers (NSCLC)
ALK, ATM, BARD1, BRAF, BRCA1, BRCA2, BRIP1, CDK12, CDK4, CDKN2A (P16INK4A), CHEK1, CHEK2 (RAD53), CTNNB1, EGFR (ERBB1), ERBB2 (HER-2, NEU), FANCL, KIT (CD117), KRAS, MAP2K1, MET, MLH1, MLH3, MSH2, MSH3, MSH6, NRAS, PALB2, PDGFRA, PIK3CA (p110-alpha), PMS1, PMS2, PTEN, RAD51B, RAD51C, RAD51D, RAD54L, RET, ROS1, TP53 (p53)
Small Cell Lung Cancers (SCLC)
NTRK1, PIK3CA (p110-alpha), PTEN, RB1, TP53 (p53)
Squamous Cell Carcinomas
BRAF, CDKN2A (P16INK4A), EGFR (ERBB1), NTRK1, PIK3CA (p110-alpha), PTEN, TP53 (p53), TSC2