Target List
Induction of Apoptosis
Death Domain Receptors
CRADDLOC708606TNFRSF10BTNFRSF10BTNF
DNA Damage & Repair
CIDEALOC695164ABL1TP53
Extracellular Apoptotic Signals
CFLARDAPK1PRKCATNFRSF25
Other Pro-Apoptotic Genes
BAK1BCL2L11BNIP1BNIP3LCASP1CASP10CASP14CASP2CASP3CASP4CASP8CD27CD70DFFAFASGADD45ALOC100426120FASLGLOC698160LOC698788PYCARDBCL10BADBAXLTAMAPK1NOD1TNFRSF10ATNFRSF9TNFSF10TNFSF8TP53BP2TRAF3
Anti-Apoptotic
AKT1BAG1BAG3BAG4BCL2A1BCL2L10BDNFBIRC3BIRC5BIRC6BNIP1BNIP2BNIP3LCD27CD40LGCFLARDAPK1FASIGF1RIL10IL2LOC100426120LOC693554BCL2BCL2L1BFARBAXCDKN1AMCL1NAIPNOL3RIPK2TNFXIAP
Regulation of Apoptosis
Negative Regulation of Apoptosis
BAG1BAG3BAG4BCL2A1BCL2L10BIRC2BIRC3BIRC6BNIP1BNIP2BNIP3LCASP3CD27CD40LGCFLARCIDEADAPK1DFFAFASIGF1RLOC100426120LOC693554LOC695164BCL2BCL2L1BFARBCL10MCL1NAIPNOL3TP53XIAP
Positive Regulation of Apoptosis
AKT1BAK1BCL2L11BNIP3LCASP1CASP10CASP14CASP2CASP4CASP8CD40CD70CRADDLOC100426120FASLGLOC698160LOC698788LOC708606PYCARDTRAF4TNFRSF10BTNFRSF10BBADBAXABL1LTALTBRNOD1RIPK2TNFTNFRSF10ATNFRSF25TNFRSF9TNFSF10TNFSF8TP53TP53BP2TRAF3TRAF5
Death Domain Receptors
CRADDDAPK1LOC698160LOC708606TNFRSF10BTNFRSF10BTNFRSF10ATNFRSF11BTNFRSF1ATNFRSF21TNFRSF25
Caspases & Regulators
Caspases
CASP1CASP10CASP14CASP2CASP3CASP4CASP5CASP7CASP8CASP9CFLARCRADDLOC698788PYCARD
Caspase Activation
APAF1BCL2L10CARD8CASP1CASP9PYCARDTNFRSF10BTNFRSF10BBAXMYCNOD1TNFRSF10ATP53
Caspase Inhibition
CD27XIAP