Target List
Covers all exons in all known transcripts of targeted genes based on the Human GRCh38 genome build
Adenocarcinomas
APC, ARID1A, ATM, AXIN2, BARD1, BAX, BMPR1A (ALK3), BRAF, BRCA1, BRCA2, BRIP1, BUB1, BUB1B, CDK12, CDKN2A (P16INK4A), CHEK1, CHEK2 (RAD53), CTNNB1, DCC, DLC1, EGFR (ERBB1), EP300, ERBB2 (HER-2, NEU), ERBB3, ESR1 (ERα), FANCL, FBXW7, FGFR1, FGFR3, FLCN, GNAS, HRAS, KIT (CD117), KRAS, MAP2K1, MCC, MET, MLH1, MLH3, MSH2, MSH3, MSH6, MUTYH, MYC, NRAS, PALB2, PDGFRA, PDGFRL, PMS1, PMS2, POLD1, POLE, PTEN, PTPN12, PTPRJ, RAD51B, RAD51C, RAD51D, RAD54B, RAD54L, RET, RNF43, SMAD4 (MADH4), SOX9, SRC, STK11 (LKB1), TCF7L2, TGFBR2, TP53 (p53)
Metastatic Colorectal Cancers
AKT1, ATM, BRAF, ERBB2 (HER-2, NEU), KRAS, MET, NRAS, PIK3CA (p110-alpha)
Mismatch Repair (MMR) Genes
EPCAM, MLH1, MSH2, MSH6, PMS2
Other Colorectal Cancer Genes
DPYD, ERCC1, TYMS, UGT1A1