Target List
Anti-Angiogenesis
Serpine1 (Pai-1), Serpinf1, Serping1
Bruch's Membrane Markers
Fn1, Mmp2, Mmp9, Timp1, Timp3
Choroidal Neovascularization
Igf1, Tgfb1, Vegfa
Drusen Markers
Apoe, C2, C3, C4a, C5, C9, Cfb, Cfh, Cfhr1, Cfi, Hmox1, Lipc, Tf, Vtn
Endothelial Function
Anxa2, Anxa5, Clu, Col14a1, Ccn2, Efemp1, Eln, Fbln5, Icam1, Nos3 (eNOS), Vim, Vwf
Inflammatory Markers
Ccl2 (Mcp-1), Il6, Plg, Tlr3, Tlr4
Oxidative Stress
Dicer1, Gstm1 (Mgst1), Gstp1, Gstt1, Hif1a, Hmox2, Nos1 (bNOS), Sod2
Retinal Pigment Epithelium Markers
Ccl11 (Eotaxin), Crp, Cryaa, Cryab, Crygd, Cx3cr1, Cxcl12, Faslg, Rho, Rlbp1, Rpe65, Sag
Other Age-Related Macular Degeneration Related Genes
Abca1, Abca4, Ace, Alb, Cp, Cst3, Ctsd, Ercc6, Fancg, Gfap, Hmcn1, Htra1, Lep (Leptin), Lpl, Pon1, Scarb1, Slc4a1, Sparc, Stmn1, Thy1, Tnmd, Vldlr