Understanding the diverse RNA world and its network of intricate interactions is one of the most important challenges facing biology today. We offer a range of tools to help you determine the functions of coding and non-coding RNAs using a variety of approaches.
Antisense LNA GapmeRs are potent antisense oligonucleotides (ASOs) that provide highly efficient knockdown of mRNA and lncRNA.
Our miRNA inhibitors and power inhibitors are highly potent, LNA-enhanced, miRNA antisense inhibitors that work by transfection or unassisted delivery.
The miRNA mimics are sophisticated, high-quality mimics that simulate naturally-occurring, mature miRNAs, and their LNA-enhanced, triple-RNA strand design ensures excellent specificity with no off-target effects from the passenger strand.
Our miRNA target site blockers (TSBs) block the interaction of a miRNA with a specific target site, and they are valuable tools for investigating the contribution of an individual target to an observed phenotype.
Our RNAi products span the full range of functional genomics knockdowns, from a single gene, to small numbers of related genes, to genome-wide, high-throughput screens.
For miRNA loss-of-function studies using LNA-enhanced antisense miRNA inhibitors
For miRNA function studies using LNA-enhanced antisense miRNA inhibitors
For miRNA loss-of-function studies using LNA-enhanced antisense miRNA inhibitors
For studies on miRNA function and gene regulation using synthetic miRNA
For studies on miRNA function and gene regulation using synthetic miRNA
Custom-designed target site blockers for studying the effects of an individual miRNA on a single target site
LNA-enhanced antisense oligonucleotides for highly effective knockdown of mRNA and lncRNA
For siRNA transfection optimization and positive control experiments in human cells
For siRNA transfection optimization and positive control experiments in mouse or rat cells
For negative control RNAi experiments
For knockdown of a reporter gene
For highly flexible, economical RNAi screening
For efficient RNAi analysis one gene at a time
For optimized, one-step siRNA transfection
For efficient gene silencing using high-purity siRNA