Target List
Carcinomas
ATM, BARD1, BRCA1, BRCA2, BRIP1, CDK12, CDK4, CHEK1, CHEK2 (RAD53), EGFR (ERBB1), ERBB2 (HER-2, NEU), ESR1 (ERα), FANCL, KIT (CD117), KRAS, MET, MLH1, MLH3, MSH2, MSH3, MSH6, PALB2, PDGFRA, PIK3CA (p110-alpha), PMS1, PMS2, RAD51B, RAD51C, RAD51D, RAD54L
Ductal Carcinomas
AR, CCND1, CDH1 (E-Cadherin), CYP2D6, FANCD2, FBXW7, FGFR1, FGFR2, MRE11, MYC, NBN, NTRK3, PPM1D, PPP2R1A, RB1CC1, SF3B1, SLC22A18, STK11 (LKB1), TP53 (p53)
ER-Positive Carcinomas
CDH1 (E-Cadherin), RB1CC1, SF3B1
HER-Positive Carcinomas
AR, CCND1, FANCD2, NTRK3, PPM1D, RB1CC1
Metastatic Breast Cancers
AKT1, BRCA1, BRCA2, ERBB2 (HER-2, NEU), ERBB3, ESR1 (ERα), MDM2, NF1, PALB2, PIK3CA (p110-alpha), PTEN
Mismatch Repair (MMR) Genes
MLH1, MSH2, MSH6, PMS2