Target List
Adenocarcinomas
APC, ARID1A, ATM, BARD1, BRAF, BRCA1, BRCA2, BRIP1, CDK12, CDKN2A (P16INK4A), CHEK1, CHEK2 (RAD53), CTNNB1, EGFR (ERBB1), ERBB2 (HER-2, NEU), ERBB3, FANCL, FBXW7, GNAS, KIT (CD117), KRAS, MAP2K1, MET, MLH1, MLH3, MSH2, MSH3, MSH6, MYC, NRAS, PALB2, PDGFRA, PMS1, PMS2, PMS2CL, POLE, PTEN, RAD51B, RAD51C, RAD51D, RAD54L, RET, RNF43, SMAD4 (MADH4), TCF7L2, TGFBR2, TP53 (p53)
Metastatic Colorectal Cancers
AKT1, ATM, BRAF, ERBB2 (HER-2, NEU), KRAS, MET, NRAS, PIK3CA (p110-alpha)
Mismatch Repair (MMR) Genes
MLH1, MSH2, MSH6, PMS2, PMS2CL
Other Colorectal Cancer Genes
DPYD, ERCC1, TYMS, UGT1A1