Target List
Anaplastic Glial Tumors
PTEN, TP53 (p53)
Astrocytomas
BRAF, CHEK2 (RAD53), FGFR1, IDH1, KRAS, PTPN11, TP53 (p53)
Ependymomas
H3-3A, NF2
Glioblastomas
APC, BCOR, BRAF, CREBBP (CBP), EGFR (ERBB1), H3-3A, IDH1, MLH1, MSH2, MTOR, NRAS, PIK3CA (p110-alpha), PMS2, PMS2CL, PTEN, TERT, TP53 (p53)
Gliomas
ACVR1 (ALK2), BRCA2, CHEK2 (RAD53), FGFR1, H3-3A, PIK3CA (p110-alpha), PTEN, TP53 (p53)
High-Grade Gliomas
BRAF, EGFR (ERBB1), IDH1
Medulloblastomas
BRCA2, CREBBP (CBP), FGFR1, IDH1, MSH2, NRAS, PIK3CA (p110-alpha), PTCH2, SUFU, TP53 (p53)
Meningiomas
NF2, PTEN
Oligodendrogliomas
IDH1, MSH2, TERT