Target List
Familial Breast-Ovarian Cancer Susceptibility
BRCA1, BRCA2, FGFR2, MAP3K1 (MEKK1), RAD51C, RAD51D, TOX3
Breast Cancers
Breast Cancer Carcinomas
ATM, BARD1, BRCA1, BRCA2, BRIP1, CHEK2 (RAD53), ERBB2 (HER-2, NEU), ESR1 (ERα), MLH1, MSH2, MSH6, PALB2, PIK3CA (p110-alpha), PMS2, RAD51C, RAD51D
Breast Cancer Ductal Carcinomas
CDH1 (E-Cadherin), FGFR2, MRE11, NBN, STK11 (LKB1), TP53 (p53)
Breast Cancer Susceptibility
BARD1, BRCA2, PALB2, RECQL, XRCC3
Metastatic Breast Cancers
BRCA1, BRCA2, ERBB2 (HER-2, NEU), ESR1 (ERα), NF1, PALB2, PIK3CA (p110-alpha), PTEN
Other Breast Cancer Genes
APC, AXIN2, SDHB, SMARCA4, TSHR
Ovarian Cancers
Ovarian Cancer Epithelial Carcinomas
ABRAXAS1, ATM, BARD1, BRCA1, BRCA2, BRIP1, CHEK2 (RAD53), ERBB2 (HER-2, NEU), MRE11, NBN, NF1, PALB2, PIK3CA (p110-alpha), PTEN, RAD51C, RAD51D, TP53 (p53)
Ovarian Cancer Mixed Adenosquamous Carcinomas
BLM, CDH1 (E-Cadherin), DICER1, FANCC, FANCM, FGFR2, RAD50, RAD51, SMARCA4, STK11 (LKB1)
Other Ovarian Cancer Genes
MLH1, RECQL, RINT1, XRCC2
Uterine Serous Carcinomas
BLM, CDH1 (E-Cadherin), DICER1, FANCC, FANCM, FGFR2, RAD50, RAD51, SMARCA4
Lynch Syndrome
EPCAM, MLH1, MSH2, MSH6, PMS2
Other Hereditary Breast & Ovarian Cancer Genes
HMMR, MUTYH, NQO2, PGR, PHB, POLD1, PRKAR1A