Target List
Th1 Genes
Th1 Markers
CCR5, CXCR3, IFNG, STAT4, TBX21
Th1 Immune Response
CCR2, CD80, EBI3, IL12B, IL18, IL1RL1 (ST2), IL27, IL27RA, IL4R (CD124), SLC11A1, SOCS5, TLR4, TLR6, TNFSF4 (OX40L), VEGFA
Other Th1-Related Genes
CD28, CD40LG, CSF2 (GM-CSF), HAVCR2, IL12RB2, IL18R1, IL2, IL2RA (CD25), IRF1, SOCS1, STAT1, TNF
Cell-Mediated Immunity
BCL6, CD27 (TNFRSF7), CD28, CD40LG, IFNG, IL10, IL12B, IL2, IL27RA, IL4, IL7R, LTA (TNFB), PTPRC, SLC11A1, STAT6, TBX21, TLR4, TNF, TNFSF4 (OX40L)
Th2 Genes
Th2 Markers
CCR4, GATA3, IL13, IL25, IL2RA (CD25), IL4, IL4R (CD124), IL5, STAT6
Th2 Immune Response
BCL6, CCR2, CD86, IL10, IL18, IL27RA, IL6, SOCS5, TNFSF4 (OX40L)
Other Th2-Related Genes
CCL11 (Eotaxin), CCL5 (RANTES), CCL7 (MCP-3), CCR3, CEBPB, GFI1, PTGDR2 (CRTH2, GPR44), ICOS, IL13RA1, IL1R1, IL9, IRF4, JAK1, MAF, NFATC1, NFATC2, PCGF2
Humoral Immunity
CD28, EBI3, IFNG, IL6, IL7, LTA (TNFB), TNF
CD4+ T-Cell Markers
CD27 (TNFRSF7), CD4, CD40LG, CD80, CD86, CREBBP (CBP), CTLA4, FASLG (TNFSF6), IL15, IL6, IL6R, IL7, JAK2, LAG3, LAT, MAPK8 (JNK1), PTPRC, TGFB3, TNFRSF8, TNFRSF9, TNFSF4 (OX40L), TYK2, YY1
Other Inflammatory Response Genes
IL24, JAK2, LTA (TNFB), SPP1
Other Immune Response Genes
IL3, SFTPD