Target List
Cell Adhesion Molecules
Cell Adhesion Molecules
APC, CD44, CDH1 (E-Cadherin), CDH11, CDH6, FAT1, FXYD5, ITGA7, PNN, SYK, VEGFA
Transmembrane Receptors
CD44, ITGA7, ITGB3, RPSA
Other Cell Adhesion Molecules
CTNNA1, FN1, MCAM, MGAT5, MTSS1
Extracellular Matrix (ECM) Molecules
Extracellular Matrix (ECM) Proteases
MMP10, MMP11, MMP13, MMP2, MMP3, MMP7, MMP9
Extracellular Matrix (ECM) Protease Inhibitors
TIMP2, TIMP3, TIMP4
Other Extracellular Matrix (ECM) Molecules
COL4A2, HPSE, SERPINE1 (PAI-1)
Cell Cycle
Regulation of the Cell Cycle
APC, BRMS1, CDKN2A (P16INK4A), HRAS, IL1B, KRAS, MTSS1, NF2, NME1 (NM23), PTEN, RB1, TGFB1, TP53 (p53), VEGFA
Cell Cycle Arrest & Checkpoints
CDKN2A (P16INK4A), MYC, RB1, TP53 (p53)
Cell Growth & Proliferation
Negative Regulation of Cell Proliferation
CDKN2A (P16INK4A), CTBP1, GNRH1, IL1B, MDM2, NF2, NME1 (NM23), SSTR2
Positive Regulation of Cell Proliferation
IGF1, IL18, TSHR, VEGFA
Growth Factors & Hormones
GNRH1, HGF, IGF1, TGFB1, VEGFA
Cytokines
CCL7 (MCP-3), CXCL12 (SDF1), IL18, IL1B, TNFSF10 (TRAIL)
Cell Surface Receptors
CXCR2, CXCR4, EPHB2, FGFR4, FLT4 (VEGFR2), KISS1R, MET, NR4A3 (NOR1), PLAUR (UPAR), RORB, SSTR2, TSHR
Other Cell Growth Genes
DENR, EWSR1, HRAS, MYC, SET, SRC, SYK, TRPM1
Apoptosis
CXCR4, HTATIP2, IL18, IL1B, TGFB1, TIMP3, TNFSF10 (TRAIL), TP53 (p53)
Transcription Factors & Regulators
CHD4, ETV4, EWSR1, HTATIP2, MTA1, MYC, MYCL, NR4A3 (NOR1), RB1, RORB, SMAD2 (MADH2), SMAD4 (MADH4), TCF20, TP53 (p53)
Other Tumor Metastasis Genes
CD82, CST7, CTSK, CTSL, KISS1, METAP2, NME4