Target List
Innate Immunity
Pattern Recognition Receptors (PRRs)
DDX58, NLRP3, NOD1 (CARD4), NOD2, TLR1, TLR2, TLR3, TLR4, TLR5, TLR6, TLR7, TLR8, TLR9
Cytokines
CCL2 (MCP-1), CCL5 (RANTES), CSF2 (GM-CSF), CXCL10 (INP10), IFNA1, IFNB1, IL18, IL1A, IL1B, IL2, CXCL8 (IL8), TNF
Other Innate Immunity Genes
APCS, C3, CASP1 (ICE), CD14, CD4, CD40 (TNFRSF5), CD40LG, CD8A, CRP, HLA-A, HLA-E, IL1R1, IRAK1, IRF3, IRF7, ITGAM, LY96 (MD-2), LYZ, MAPK1 (ERK2), MAPK8 (JNK1), MBL2, MPO, MX1, MYD88, NFKB1, NFKBIA (IκBα, MAD3), STAT1, TICAM1 (TRIF), TRAF6
Adaptive Immunity
Th1 Markers & Immune Response
CCR5, CD80, CXCR3, IFNG, IL18, IL23A, SLC11A1, STAT4, TBX21, TLR4, TLR6
Th2 Markers & Immune Response
CCR4, CCR8, CD86, GATA3, IFNB1, IL10, IL13, IL18, IL4, IL5, IL6, NOD2, STAT6
Th17 Markers
CCR6, IL17A, RORC, STAT3
Treg Markers
CCR4, CCR8, FOXP3, IL10
T-Cell Activation
CD80, CD86, ICAM1, IFNG, IL23A, IL6, SLC11A1
Cytokines
CCL2 (MCP-1), CCL5 (RANTES), CSF2 (GM-CSF), CXCL10 (INP10), IFNA1, IFNG, IL10, IL13, IL17A, IL18, IL2, IL23A, IL4, IL5, IL6, CXCL8 (IL8), TNF
Other Adaptive Immunity Genes
CD4, CD40 (TNFRSF5), CD40LG, CD8A, CRP, FASLG (TNFSF6), HLA-A, IFNAR1, IFNGR1, IL1B, IL1R1, IRF3, IRF7, ITGAM, JAK2, MAPK8 (JNK1), MBL2, MX1, NFKB1, RAG1, STAT1
Humoral Immunity
C3, CCL2 (MCP-1), CCR6, CRP, IFNB1, IFNG, IL6, MBL2, NOD2, TNF
Inflammatory Response
APCS, C3, CCL5 (RANTES), CRP, FOXP3, IL1A, IL1B, IL4, IL6, MBL2, STAT3, TNF
Defense Response to Bacteria
IFNB1, IFNG, IL23A, IL6, LYZ, MBL2, MYD88, NOD1 (CARD4), NOD2, SLC11A1, TLR1, TLR3, TLR4, TLR6, TLR9, TNF
Defense Response to Viruses
CD4, CD40 (TNFRSF5), CD86, CD8A, CXCL10 (INP10), DDX58, HLA-A, IFNAR1, IFNB1, IL23A, IL6, IRF3, NLRP3, TICAM1 (TRIF), TLR3, TLR7, TLR8, TYK2