Target List
Differentially Methylated Promoters
AFF1, ATM, CADM1 (TSLC1), CCND1, CDH1 (E-Cadherin), CDH13, CDKN1C (p57Kip2), CDKN2B (p15INK4b), CDKN2C (p18-INK4C), DAPK1, DLC1, FHIT, GSTP1, HIC1, HRK, ID4, LRP1B, MLH1, MYOD1, RASSF1, RBP1, SLC19A1, TIMP2, TIMP3
Diffuse Large B-Cell Lymphoma Survival
ASB13, BCL6, ITPKB, LMO2, LRMP, MYBL1, PAG1, PTK2 (FAK), TTC9, VGLL4
Follicular Lymphoma Survival
C1QA, CCR1, F8, FCGR1A, FLT3LG, STAT4, TLR5, TNFRSF1B, TNFSF13B
Lymphoma Therapeutic Targets
BCL6, BIRC5, BTK, CD22, CD40 (TNFRSF5), CD80, CXCR4, FCGR1A, HSP90AA1, MCL1, MS4A1, MTOR, NOTCH1, PARP1 (ADPRT1), PTK2 (FAK), SRC, SYK, TGFB1, TNFSF13B
Inflammatory Response
C1QA, CCR1, CD40 (TNFRSF5), CD40LG, CSF3 (GCSF), CXCR4, F8, IL6, NFKB1, TGFB1, TLR5, TNF, TNFRSF1B
Immune System Processes
BCL6, C1QA, CADM1 (TSLC1), CD2, CD4, CD40 (TNFRSF5), CD5, CD79A, CD80, FCER2, IFNG, IL2, IL6, ITPKB, PDLIM7, PTPRC, SYK, TGFB1, TNFSF13B
T-Cell Differentiation
BCL2, CD3D, CD4, CD8A, ITPKB, IL2, PTPRC, SYK, TGFB1, TP53 (p53)
Cell Adhesion Molecules
BCL2, CADM1 (TSLC1), CCR1, CD2, CD22, CD34, CD4, CD40LG, CD47, CD8A, CDH1 (E-Cadherin), CDH13, DLC1, F8, IL2, NCAM1, PTPRC, SRC, SYK, TNF
Cell Cycle
ATM, BCL2, BIRC5, CCND1, CDKN1C (p57Kip2), CDKN2B (p15INK4b), CDKN2C (p18-INK4C), ID4, IFNG, MKI67, MLH1, MYC, RASSF1, TGFB1, TP53 (p53)
AKT & PI3 Kinase Signaling
ALK, BCL2, BTK, CCND1, CCR1, CD2, CD4, CD40 (TNFRSF5), CD40LG, CSF3 (GCSF), CXCR4, HSP90AA1, IL2, IL6, MTOR, PTK2 (FAK), SYK, TGFB1, TIMP2, TIMP3, TNFRSF1B, TNFSF13B, TP53 (p53)
Gene Fusion
ALK, MME
DNA Damage & Repair
DNTT