Target List
Apoptosis
CCL2 (MCP-1), MAOA, NDUFB5, NPPA, NPPB, NPR1, PDE3A, SNCA, THBS2, UBB, ZYX
Cardiac Remodeling
AEBP1, ANXA4, COL11A1, COL1A1, COL3A1, DCN, DMD, F2R (PAR1), FN1, GJA1 (CX43), MMP13, MT1X, REN, RTN4, SERPINA3, TNNI3, TNNT2
Cell Cycle
CCND1, CDKN1B (P27KIP1), G0S2, RARRES1 (TIG1)
Cell Growth
ACE, SFRP4, SPOCK1, CCN2, PTN
Sarcomere Structural Proteins
ACTC1, CRYAB, CRYM, MYH10, MYH6, NEBL, POSTN
Signal Transduction
DUSP6, PDE3B, PDE7A, RASSF1, FRZB (FRP-3), HMGCL, HMGCR, MAPK1 (ERK2), MAPK8 (JNK1), PDE5A, SLC12A1, ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3, AGTR1, NPR2, NPR3, AR, EPOR, NR3C1 (GRL), NR3C2
Stress & Immune Response
C6, CCL2 (MCP-1), CCL11 (Eotaxin), CCL18 (PARC), S100A1
Transcriptional Regulation
CREB5, CREM, ENAH, HMGN2, KLHL3, MSI2, NFIA, NKX2-5, STAT1, TCF4
Transporters
ATP2A2, ATP5F1A