Clec1a Gene Summary [Mouse]
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; brain; gut; heart ventricle; and lung. Human ortholog(s) of this gene implicated in aspergillosis. Orthologous to human CLEC1A (C-type lectin domain family 1 member A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Clec1a |
| Official Name | C-type lectin domain family 1, member a [Source:MGI Symbol;Acc:MGI:2444151] |
| Ensembl ID | ENSMUSG00000033082 |
| Bio databases IDs | |
| Aliases | C-type lectin domain family 1, member a |
| Synonyms | 5930406N14Rik, CLEC-1, C-type lectin domain family 1 member A, C-type lectin domain family 1, member A, RGD1566110 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Clec1a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- Lectin C-type domain
- protein binding
- transmembrane receptor
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- intracellular space
- cellular membrane
- perinuclear space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Clec1a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- cell surface receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- transmembrane signaling receptor activity
- protein binding
- carbohydrate binding