Detection Probes for Localization Studies
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Differentiate splice variants, isoforms and small mutations
Due to their LNA enhancement, our detection probes exhibit unprecedented thermal stability when hybridized to their complement. This much higher affinity – compared to traditional DNA or RNA oligos – helps overcome the difficulties of studying very short sequences. LNA oligos have greatly improved, and in many cases enabled, specific and sensitive detection of non-coding RNA and other small RNA molecules and provide an exceptionally high signal-to-noise ratio.
Related Applications and Insights
LNA technology center
Discover how the high affinity of locked nucleic acids (LNA) to their targets helps overcome the difficulties of studying very short DNA and RNA fragments
Detection/ISH custom builders
Create high-performance mRNA/lncRNA and miRNA detection probes for your ISH, Northern blotting or localization studies
Products (3)
miRNA Detection Probes
miRCURY LNA miRNA Detection ProbesFor ultra-sensitive and specific miRNA detection by in situ hybridization (ISH) or Northern blotting
miRCURY LNA miRNA Custom Detection ProbesFor ultra-sensitive and specific detection of novel miRNA sequences by in situ hybridization (ISH) or Northern blotting
mRNA Detection Probes
Custom LNA mRNA Detection ProbesFor ultra-sensitive detection of mRNA and lncRNA by in situ hybridization and Northern blotting