Coro7 Gene Summary [Mouse]
Predicted to enable actin binding activity. Acts upstream of or within several processes, including Golgi organization; actin filament organization; and establishment of cell polarity. Located in Golgi apparatus and membrane. Is expressed in hemolymphoid system; nervous system; neural retina; and small intestine. Orthologous to human CORO7 (coronin 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Coro7 |
| Official Name | coronin 7 [Source:MGI Symbol;Acc:MGI:1926135] |
| Ensembl ID | ENSMUSG00000039637 |
| Bio databases IDs | |
| Aliases | coronin 7 |
| Synonyms | 0610011B16Rik, COR7, coronin 7, Coronin family 70-kd wd-repeat tumor antigen, Coronin family 70-kd wd-repeat tumour antigen, CRN7, LOC100910951, LOC108348151, POD1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Coro7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Type of WD40 repeat
- WD40 repeats
- actin binding
- WD domain, G-beta repeat
- WD40
- protein binding
- Domain of unknown function (DUF1899)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Golgi Apparatus
- trans Golgi network
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Coro7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of hippo signaling cascade
- Golgi organization
- actin filament polymerization
- protein transport
- establishment of cell polarity
- cell migration
- Golgi to endosome transport
Cellular Component
Where in the cell the gene product is active
- trans-Golgi network
- membrane
- cytoplasmic vesicle
- cytosol
- Golgi membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- protein binding
- actin binding