dPCR LNA Mutation Assays

Pour la détection de mutations de séquences d’ADN spécifiques en lien avec le cancer et l’oncogenèse

  • La conception duplex des dosages permet de détecter les séquences mutées et de type sauvage
  • Choix entre les combinaisons de colorants fluorescents FAM + HEX ou Atto 550 + ROX
  • Les amorces et sondes aux performances améliorées par des LNA accroissent la spécificité et la sensibilité des dosages
  • Dosages testés par dPCR en laboratoire humide, disponibles pour plus de 200 cibles
  • Adaptés à une utilisation avec l’ADN tumoral circulant, les biopsies liquides, les tissus FFPE et autres échantillons de tissus
  • Conçus pour une utilisation avec les QIAcuity Probe PCR Kits

Product

Product List13 products

GeneGlobe ID: DMH0000156 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 785 Human
AA Mutation: p.D835H
Nucleotide Mutation: c.2503G>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000158 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 303886 Human
AA Mutation: p.N676K
Nucleotide Mutation: c.2028C>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000160 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 25248 Human
AA Mutation: p.G831E
Nucleotide Mutation: c.2492G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000154 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 784 Human
AA Mutation: p.D835V
Nucleotide Mutation: c.2504A>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000500 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 28040 Human
AA Mutation: p.D324N
Nucleotide Mutation: c.970G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000503 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 28047 Human
AA Mutation: p.R834Q
Nucleotide Mutation: c.2501G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000152 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 783 Human
AA Mutation: p.D835Y
Nucleotide Mutation: c.2503G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000168 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 787 Human
AA Mutation: p.D835E
Nucleotide Mutation: c.2505T>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000009 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 116249 Human
AA Mutation: p.V491L
Nucleotide Mutation: c.1471G>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000281 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 28042 Human
AA Mutation: p.S451F
Nucleotide Mutation: c.1352C>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000494 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 19692 Human
AA Mutation: p.Y842C
Nucleotide Mutation: c.2525A>G
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000174 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 19522 Human
AA Mutation: p.V592A
Nucleotide Mutation: c.1775T>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000496 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay FLT3 788 Human
AA Mutation: p.D835E
Nucleotide Mutation: c.2505T>G
dPCR wet-lab validated
Product Specification
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Resources

Instrument User Manuals (1)
Quick-Start Protocols (1)
Safety Data Sheets (1)
Application Notes (1)
Digital PCR (dPCR) is a powerful technique that detects and quantifies ultra-rare mutations in a high background of wild-type cfDNA down to 0.1% variant allele frequency. Here, we describe end-to-end manual and automated workflows that enable accurate detection and absolute quantification of ultra-rare PIK3CA variants in cfDNA using the QIAcuity Digital PCR System.
Certificates of Analysis (1)