Target List
Neurotransmitter Receptors
Dopamine Receptors
Drd1, Drd2, Drd3, Drd4, Drd5
Serotonin (5-Hydroxytryptamine) Receptors
Htr1a, Htr1b, Htr1d, Htr1f, Htr2a, Htr2b, Htr2c, Htr3a, Htr3b, Htr4, Htr5a, Htr6, Htr7
Neurotransmitter Synthesis & Degradation
Dopamine Metabolism
Comt, Dbh, Ddc, Maoa, Th
Serotonin Metabolism
Maoa, Maob, Tdo2, Tph1, Tph2
Dopamine & Serotonin Transporters
Slc6a3 (Dat), Slc6a4 (Sert)
Signal Transduction
cAMP & Protein Kinase A Signaling
Adcy1, Adcy2, Adcy3, Adcy5, Cacna1a, Casp3, Cdk5, Creb1, Dusp1 (Ptpn16), Fos, Prkaca, Mapk1 (Erk2), Ppp1r1b (Darpp32)
AKT & PI3 Kinase Signaling
Pik3ca (p110alpha), Pik3cg, Akt1, Akt2, Akt3, Gsk3a, Gsk3b
Phospholipase A2 Pathway
Alox12, Cyp2d22, Pde4a, Pde4b, Pde4c, Pde4d, Pde10a, Pla2g5
Phospholipase C Signaling
Itpr1, Plcb1, Plcb2, Plcb3
G-Protein Coupled Receptor Regulation
Adrb1, Adrb2, Grk2, Grk3, App, Arrb1, Arrb2, Grk4, Grk5, Grk6, Snca, Sncaip
Dopamine & Serotonin Gene Targets
Bdnf, Ephb1, Gdnf, Gfap, Nr4a1 (nur77), Nr4a3 (Nor1), Pdyn, Ptgs2 (Cox2), Slc18a1, Slc18a2 (Vmat2), Syn2