Target List
Differentiation & Development
Growth Factors
ANGPTL4, BMP4, CCN2, FGF20, FGF4, FGF9, GDF5 (CDMP-1), GDNF, IGF1, IGF2, IL6, JAG1, TGFB3, VEGFA
Transcription Factors
CDKN2A (P16INK4A), EGR1, NANOG, POU5F1 (OCT4), PPARD, RUNX2, SIX1, SOX2, SOX9, TBXT (Brachyury)
Other Differentiation & Development Genes
ANTXR1, CCND1, CCND2, CDH1 (E-Cadherin), CDON, DAB2, DLK1, EFNB1, EGFR (ERBB1), FN1, FST, GJA1 (CX43), ID2, MET, MMP9, NRCAM, NRP1, NTRK2, PDGFRA, SMO, TWIST1
Calcium Binding & Signaling
BGLAP, CACNA2D3, CCND1, CUBN, EGFR (ERBB1), LRP1, MMP2, MMP7, MMP9, PTGS2 (COX2), WNT3A, WNT5A, WNT9A
Cell Adhesion Molecules
ABCB1 (MDR1, PGY1), BGLAP, CCN2, CD44, CDH1 (E-Cadherin), EGFR (ERBB1), FGF4, NRCAM, SOX9
Cell Migration
CCN2, CD44, EFNB1, EGFR (ERBB1), FGF7, FN1, GDNF, IGF1, IL6, IRS1, JAG1, MMP9, NRCAM, NRP1, PDGFRA, PLPP3, PPARD, SIX1, SMO, TWIST1, VEGFA
Cell Cycle
AHR, BIRC5, CCND1, CCND2, CDKN2A (P16INK4A), EGFR (ERBB1), FOSL1 (FRA-1), ID2, IGF1, IGF2, MYC, PTGS2 (COX2), SOX2
Proteases
DPP10, MMP2, MMP7, MMP9, PLAUR (UPAR)
Signal Transduction
WNT Signaling
AXIN2, BTRC (bTrCP), CCN4, CCN5, DKK1, FGF9, FZD7, LEF1, LRP1, PLPP3, SFRP2, TLE1, WNT3A, WNT5A, WNT9A
TGFβ Signaling
BMP4, FST, GDF5 (CDMP-1), ID2, TGFB3
Hedgehog Signaling
PTCH1, SMO
Notch Signaling
JAG1
Transcription Factors
WNT Signaling
LEF1, TCF7, TCF7L1, TCF7L2
Other Transcription Factors
AHR, CDKN2A (P16INK4A), CEBPD, EGR1, ETS2, FOSL1 (FRA-1), KLF5, MYC, NANOG, PITX2, POU5F1 (OCT4), PPARD, RUNX2, SIX1, SOX2, SOX9, TBXT (Brachyury), TCF4