Differentiate splice variants, isoforms and small mutations
Due to their LNA enhancement, our detection probes exhibit unprecedented thermal stability when hybridized to their complement. This much higher affinity – compared to traditional DNA or RNA oligos – helps overcome the difficulties of studying very short sequences. LNA oligos have greatly improved, and in many cases enabled, specific and sensitive detection of non-coding RNA and other small RNA molecules and provide an exceptionally high signal-to-noise ratio.