Target List
G-Protein Coupled Receptors (GPCRs)
Metabotropic Glutamate & GABA-Like Receptors
Casr, Grm1, Grm2, Grm4, Grm5, Grm7
Rhodopsin-Like Receptors
Adora2a, Adrb1, Adrb2, Agt, Agtr1a, Agtr1b, Agtr2, Agtrap, Drd1, Drd2, Galr2, Lhcgr, Lpar1, Lpar2, Oprd1, Oprk1, Ptgdr, Rho, Tshr
Secretin-Like Receptors
Adora2a, Adgrb1, Calcr, Calcrl, Crhr1, Crhr2, Gcgr, Sctr
Other G-Protein Coupled Receptors (GPCRs)
Edn1, S1pr1, S1pr2, S1pr3
G-Protein Coupled Receptor Signaling Pathways
Dopamine Receptor Signaling
Drd1, Drd2, Oprd1
G-Protein & cAMP / Protein Kinase A Signaling
Adcy5, Adora2a, Adrb1, Adrb2, Calcr, Calcrl, Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl2 (MCP-1), Col1a1, Crhr1, Crhr2, Cyp19a1, Drd1, Edn1, Galr2, Gcgr, Gnaq, Gnas, Grm2, Grm4, Il1r1, Il1r2, Lhcgr, Nos2 (iNos), Oprd1, Oprk1, Ptgs2 (Cox2), Rgs2, Tshr, Ucp1, Vegfa
G-Protein & IP3 / Phospholipase C Signaling
Agtr1a, Agtr1b, Calcrl, Casr, Edn1, Gnaq, Grm5, Lpar1, Lpar2, Pik3cg
Metabotropic Glutamate Receptor Signaling
Grm1, Grm2, Grm4, Grm5, Grm7
Neuropeptide Signaling
Adgrb1, Oprd1
Adenosine Receptor Signaling
Adcy5, Adora2a
Calcium Signaling (PKC, NFAT, etc.)
Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl4 (Mip-1b), Col1a1, Egr1, Elk4, Kcnh8 (Elk1), Ptgs2 (Cox2)
PKC Signaling (Calcium, MEK, etc.)
Agtr2, Col1a1, Dusp14, Egr1, Fgf2 (bFGF), Fos, Il1r1, Il1r2, Jun, Junb, Mmp9, Myc, Nos2 (iNos), Prkca, Ptgs2 (Cox2), Rgs2, Serpine1 (Pai-1), Socs1
Tyrosine Kinase Signaling
Adrb2, Akt1, Ccl4 (Mip-1b), Ccn2, Pdpk1, Prkca, Rgs2, Socs1, Ywhaz
Protein Serine / Threonine Kinase Signaling
Akt1, Cdkn1b (p27Kip1), Pdpk1, Ptgdr
MAP Kinase Signaling
Adrb2, Agt, Fgf2 (bFGF), Grm1, Grm4, Prkca, Tnf, Ucp1
PI3 Kinase Signaling
Akt1, Bcl2, Bcl2l1 (Bcl-XL), Bcl2l1 (Bcl-XL), Bcl2l1 (Bcl-XL), Ccnd1, Cdkn1b (p27Kip1), Cflar (Casper), Pdpk1, Pik3cg, Ptgs2 (Cox2)
Nitric Oxide / cGMP Signaling
Agtr2, Nos2 (iNos), Ptgs2 (Cox2), Tnf
RHO Signaling
Cdkn1b (p27Kip1), Ccn2, Fos, Il1b, Ptgs2 (Cox2), Rho, Serpine1 (Pai-1)
IκB Kinase / NFκB Cascade
Agt, Cflar (Casper), Icam1, Il1b, Il2, Max, Nos2 (iNos), Ptgs2 (Cox2), Tnf, Vcam1
JAK / STAT Signaling
Ccl2 (MCP-1), Ccl2 (MCP-1), Ccl2 (MCP-1), Cdkn1a (p21Cip1, Waf1), Socs1
Other G-Protein Coupled Receptor Signaling Genes
Arrb1, Arrb2, Ccne1, Ccne2