Target List
Up-Regulated in Neurotoxicity
Apoptosis
Bag4, Bik, Casp7, Cdkn1a (Cip1, Waf1), Cidea, Cideb, Cradd, Dapk1, Fas, Faslg, Gch1, LOC100909750 (Abl1), Sod2, Tnfrsf10b (QuantiNova Symbol: AABR07018323.1), Tnfrsf11b (Opg), Tp53 (p53), Traf4, Ywhae
Neuron Development
Casp7, Drp2, Ereg, Heph, Il10, Mmp9, Plp1, Sod2, Tp53 (p53), Ywhae
Metabolism (Regulation & Mechanism)
Arg2, Arrb1, Atf4, Cdkn1a (Cip1, Waf1), Cidea, Ddit3 (Gadd153, Chop), Dynll1, Ereg, Gal, Gucy1a1, Hsp90aa1, Il10, LOC100909750 (Abl1), Nfkb1, Pou1f1 (Pit-1), Pygb, Rasd1, Slc16a3, Sod2, Tnfrsf10b (QuantiNova Symbol: AABR07018323.1), Tp53 (p53), Traf2, Usp7, Ywhae
Nitric Oxide Response
Arg1, Arg2, Dynll1, Gch1, Gucy1a1, LOC100361087 (Nos1ap), Nosip, Nostrin, Rasd1, Slc16a3
Signal Transduction
Arrb1, Cd8b, Cdkn1a (Cip1, Waf1), Cidea, Cideb, Dapk1, Ddit3 (Gadd153, Chop), Faslg, Gpr37, Gucy1a1, Hspa5 (Grp78), Il10, LOC100909750 (Abl1), Rasd1, Tnfrsf10b (QuantiNova Symbol: AABR07018323.1), Tp53 (p53), Traf2, Ywhae
Ion Transporters
Camk2d, Clcn5, Clcnkb, Heph, Sfxn5, Trpm1, Trpm4
Other Genes Up-Regulated in Nephrotoxicity
Angptl4, Pappa1, Pdia4
Down-Regulated in Neurotoxicity
Apoptosis
Lta (Tnfb), Nol3, Tnfrsf25 (Dr3), Xiap
Neuron Development
Bdnf, Kit (Cd117), Lefty2 (Ebaf), Lta (Tnfb), Notch4, Sema3b
Metabolism (Regulation & Mechanism)
Bdnf, Camk2a, Ccnd1, Cdo1, Drd2, Eif2ak3, Galc, Grin1, Gsr, Htr1a, Kit (Cd117), Notch4, Prim2, Tph1, Txnip, Tyrp1
Signal Transduction
Birc2 (c-IAP2), Ccnd1, Drd2, Eif2ak3, Gsn, Htr1a, Kit (Cd117), Tacr1
Ion Transporters
Drd2, Grin1
Other Genes Down-Regulated in Neurotoxicity
Col12a1, Egln3, Htr3a, Nup50