Target List
Th2 Cytokines & Related Genes
Areg, Ccl11 (Eotaxin), Ccl12 (MCP-5, Scya12), Ccl17 (Tarc), Ccl22 (Mdc), Ccl24 (Mpif-2, Eotaxin-2), Ccl26 (Eotaxin-3), Ccl4 (Mip-1b), Ccl5 (Rantes), Csf2 (GMCSF), Ptgdr2 (Crth2), Icos, Ifng, Il10, Il12a, Il12b, Il13, Il17a, Il18, Il21, Il25, Il3, Il33, Il4, Il5, Il9, Pdcd1 (PD-1), Pdcd1 (PD-1), Pmch, Tgfb1, Tnfsf4 (Ox40l), Tslp
Cytokine & Chemokine Receptors
Ccr3, Ccr4, Ccr8, Cd40lg, Crlf2, Csf3r (G-CSFR), Ifngr2, Il13ra1, Il13ra2, Il17rb, Il1rl1 (St2), Il2ra (Cd25), Il3ra, Il4ra (Cd124), Il5ra (Cd125), Tnfrsf4 (Ox40)
Transcription Factors
Bcl6, Ets1, Foxp3, Gata3, Maf, Pparg, Rorc, Satb1, Stat5a, Stat6, Tbx21
Mast Cells & IgE
Cma1, Cpa3, Fcer1a, Kit (Cd117), Kitl (Scf), Ms4a2, Tpsb2
Eosinophils
Rnase2a, Rnase2b, Epx, Itga4 (Cd49d), Prg2
Natural Killer (NK) Cells
Ifng, Il12a, Il12b, Il13, Il18, Il21, Il33
Alternatively Activated Macrophages
Arg1, Chil1, Chia1, Mrc1, Retnlg
Asthma
Adam33, Adrb2, Alox5, Clca1, Cysltr1, Ltb4r1, Mmp9, Muc5ac, Postn