Target List
Apoptosis
Casp1 (Ice), Ccl12 (MCP-5, Scya12), Egr3, Il1b, Il2ra (Cd25), Il6, Itgb2, Lcn2 (Ngal), Sod2, Tnf
Inflammation
C3, Ccl11 (Eotaxin), Ccl20 (Mip-3a), Ccl25 (Teck), Ccl5 (Rantes), Ccr1, Ccr2, Ccr5, Cx3cl1, Cxcl1 (Gro1), Cxcl10 (Inp10), Cxcl11 (Itac, Ip9), Cxcl11 (Itac, Ip9), Cxcl11 (Itac, Ip9), Cxcl2 (Gro2), Cxcl3, Cxcl9 (Mig), Cxcr1, Fpr1, Il13, Il17a, Il1b, Il2ra (Cd25), Il23a, Il5, Il6, Itgb2, Ltb, Lyz1, S100a8, S100a9, Saa3, Sele, Stat3, Tnf
Immunity
Humoral Immunity
Ccl12 (MCP-5, Scya12), Il6, Lyz1
Innate Immunity
C3, Casp1 (Ice), Cd55, Cr2, Il1rn, Irf5, Isg15, Lcn2 (Ngal), Nod2, Nos2 (iNos), Saa3, Tyk2
Adaptive Immunity
Ccl11 (Eotaxin), Ccr2, Ccr5, Ccr9, Cxcr3, H2-Aa, H2-Eb1, Ifng, Il13, Il17a, Il2ra (Cd25), Il5, Il6, Irf5, Stat1
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Ccl12 (MCP-5, Scya12), Ccr1, Ccl11 (Eotaxin), Cldn8, Col1a2, Csta1, Cx3cr1, Cxcl12, Cxcr3, Itgb2, Mmp1a, Mmp10, Mmp12, Mmp3, Mmp7, Pecam1, Sele, Sell (Lecam-1), Timp1, Vwf
Unfolded Protein Response
Hsp90b1, Hspa5 (Grp78), Ubd
Digestive Secreted Proteins
Gcg, Muc1 (mucin), Reg1, Reg2, Tff1 (Ps2)
Metabolism
Adh1, Aldob, Pck1, Tdo2
Other Crohn's Disease Genes
Abcb1a (Mdr1), Atg16l1, Chil1, Edn3, Nr3c2, Selenbp1