Target List
ATM / ATR Signaling
Atm, Bard1, Brca1, Cdc25a, Chek2, Csnk2a2, Fancd2, Hus1, Parp1 (Adprt1), Parp2, Rad1, Rad17, Rad50, Rad9a (Rad9), Rnf8, Smc1a, Topbp1, Tp53 (p53)
DNA Damage & Repair
Nucleotide Excision Repair (NER)
Brca2, Dclre1a, Ddb2, Ercc1, Ercc2 (Xpd), Fancc, Lig1, Nthl1, Ogg1, Pcna, Pold3, Pole, Rpa1, Sirt1 (QuantiNova Symbol: AABR07044925.1), Tp53 (p53), Xpc
Base Excision Repair (BER)
Apex1, Fen1, Lig1, Mbd4, Mpg, Nthl1, Ogg1, Parp1 (Adprt1), Parp2, Pcna, Pole, Tp53 (p53), Ung, Wrn, Xrcc1
Mismatch Repair (MMR)
Exo1, LOC100909750 (Abl1), Mlh1, Mlh3, Msh2, Msh3, Pcna, Pms1, Pms2
Double-Strand Break (DSB) Repair
Atm, Blm, Brca1, Brca2, Hus1, Lig1, Mlh1, Mre11a, Nbn (Nbs1), Prkdc, Rad50, Rad51, Rad52, Rpa1, Tp53bp1, Xrcc2, Xrcc6
Other DNA Repair Genes
Atrx, Bard1, Bcl3, Chek2, Fanca, Fancd2, Fancg, Gadd45a, Gadd45g, Mgmt (Agt), Polh, Poli, Pttg1, Rad1, Rad17, Rad18, Rad21, Rad51b, Rad51c, Rad9a (Rad9), Rev1, Rnf8, Smc1a, Smc3, Stt3a, Sumo1, Topbp1, Wrnip1
Apoptosis
Atm, Bard1, Bax, Bcl3, Brca1, Cdkn1a (Cip1, Waf1), Chek2, Csnk2a2, LOC100909750 (Abl1), Ppp1r15a (Gadd34), Prkdc, Rad21, Rad9a (Rad9), Sirt1 (QuantiNova Symbol: AABR07044925.1), Terf1, Tp53 (p53)
Cell Cycle
Atm, Cdc25a, Cdc25c, Cdkn1a (Cip1, Waf1), Chek2, Ddit3 (Gadd153, Chop), Mif (QuantiNova Symbol: LOC103694877), Ppm1d (Wip1), Ppp1r15a (Gadd34), Terf1, Tp53 (p53)