Target List
Neuronal Migration
ASCL1, CDK5R1, DCX, DRD2, NDN, NEUROG2, NRCAM, NTN1, PAFAH1B1, ROBO1, SLIT2
Cell Differentiation
Neuronal Differentiation
ASCL1, BDNF, BMP2, BMP4, CDK5R1, CDK5RAP2, HES1, HEYL, MEF2C, NEUROD1, NEUROG1, NEUROG2, NOG, NRCAM, OLIG2, PAFAH1B1, PAX3, POU4F1, RTN4, SOX2
Neuronal Cell Fate Determination
ASCL1, NTF3, OLIG2, SOX2
Other Cell Differentiation Regulatory Genes
HDAC4, MDK, NRG1 (HGL), TENM1, PAX5, PAX6
Synaptic Functions
Regulation of Synaptic Plasticity
ADORA1, APOE, BDNF, DRD2, GRIN1, NF1, S100B
Synaptic Transmission
APOE, CHRM2, CREB1, DLG4 (PSD95), DRD2, FGF2 (BFGF), GRIN1, PAFAH1B1, SOD1, TH
Synaptogenesis
ACHE, NRCAM, POU4F1
Axonogenesis
APBB1, APP, DCX, DRD2, ERBB2 (HER-2, NEU), MAP2, NOTCH1, NRCAM, PARD3, POU4F1, S100A6, S100B
Growth Factors & Cytokines
Growth Factors
ARTN, BDNF, EGF, FGF2 (BFGF), GDNF, GPI, MDK, NDP, NRG1 (HGL), PTN, S100A6, VEGFA
Cytokines
BMP2, BMP4, BMP8B, CXCL1 (GRO1, GROa, SCYB1), GPI, IL3, MDK, PTN, TGFB1
Apoptosis
ADORA1, ADORA2A, ALK, APOE, BCL2, EP300, GDNF, NOTCH2, NTN1, PAX3, RTN4, S100B, VEGFA
Cell Adhesion Molecules
DLL1 (DELTA1), EFNB1, NRCAM, NRP1, NRP2, RAC1, ROBO1, SLIT2, TNR
Cell Cycle
APBB1, EP300, HDAC4, MDK, KMT2A, NDN, PARD3, PTN
Signal Transduction
Notch Signaling
APP, ASCL1, DLL1 (DELTA1), HES1, HEY1, HEY2, HEYL, NOTCH1, NOTCH2, NRG1 (HGL)
WNT Signaling
DVL3, NDP, SHH
TGFβ Signaling
BMP2, BMP4, BMP8B, TGFB1
G-Protein Coupled Receptor Signaling
ADORA1, ADORA2A, CHRM2, CXCL1 (GRO1, GROa, SCYB1), DRD2
Transcription Factors & Cofactors
APBB1, ASCL1, CREB1, EP300, FLNA, HES1, HEY1, HEY2, HEYL, MEF2C, KMT2A, NDN, NEUROD1, NEUROG1, NEUROG2, NR2E3, PAX3, PAX5, PAX6, POU3F3, POU4F1, SOX2, SOX8, STAT3