Target List
Myelination
Cd9, Hexb, Ifng, Mal, Mbp, Ntf3, Plp1, Pmp22, Sod1, Tgfb1
T-Cell Activation & Signaling
Adam17 (Cd156b), Apc, Cd28, Cd4, Egr1, Foxp3, Icam1, Ifng, Il10, Il18, Il1b, Il2ra (Cd25), Il6, Il6st (Gp130), Mapk1 (Erk2), Sod1, Tgfb1, Vcam1
Adaptive Immunity
Adam17 (Cd156b), C1s, Cd40, Foxp3, Icam1, Ifng, Il10, Il18, Il1b, Il6st (Gp130), Tgfb1, Vegfa
Cytokines & Chemokines
Ccl12, Ccl3 (Mip-1a), Ccl5 (Rantes), Ccl7 (Mcp-3), Csf1 (Mcsf), Cxcl10 (Inp10), Cxcl11 (I-Tac, Ip-9), Cxcl9, Faslg, Ifng, Il10, Il18, Il1b, Il6, Lta (Tnfb), Tgfb2, Tnf, Vegfa
Inflammation
Regulation of Inflammation
Ccl5 (Rantes), Ednra, Gpx1, Il6, Il6st (Gp130), Jak2, Tnfrsf1a (Tnfr1)
Inflammatory Response
C1s, Ccl12, Ccl3 (Mip-1a), Ccl7 (Mcp-3), Ccr1, Ccr5, Cd40, Cd44, Cxcl10 (Inp10), Cxcl11 (I-Tac, Ip-9), Cxcl9, Fn1, Hif1a, Il10, Il13, Il1b, Il2ra (Cd25), Itgb2, Nfkb1, Stat3, Tgfb1, Tnf, Tnfrsf1b
Apoptosis
Neuronal Apoptosis
Akt1s1 (Pras40), Bax, Bcl2, Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Erbb3, Gpx1, Jak2, Ntf3, Sod1, Tgfb2, Tnf
Other Apoptosis Genes
Adam17 (Cd156b), Il10, Mapk1 (Erk2), Tnfrsf1b, Il6st (Gp130), Hdac1, Raf1, Apc, App, Ccl12, Cd28, Faslg, Ifng, Il1b, Il2ra (Cd25), Il6, Itgb2, Mmp9, Nfkb1, Tgfb1, Tnfrsf1a (Tnfr1), Adm, Cd44, Lta (Tnfb), Mal, Vegfa
Cell Adhesion Molecules
Adam17 (Cd156b), Apc, App, Bcl2, Ccl12, Ccl5 (Rantes), Ccr1, Cd4, Cd44, Cd9, Csf1 (Mcsf), Cxcr3, Erbb3, Ezr, Fn1, Icam1, Il18, Il1b, Itgb2, Jak2, Mag, Map2k1 (MEK1), Tgfb1, Tgfb2, Tnf, Vcam1
Cellular Stress
Adm, Bcl2, Gpx1, Hif1a, Ifng, Il1b, Jak2, Ptpn11, Sod1, Tgfb2, Tnf
Receptors
Ccr1, Ccr5, Cd28, Cd4, Cd40, Cd44, Cxcr3, Ednra, Epha1, RT1-Db1, Icam1, Il2ra (Cd25), Il6st (Gp130), Itgb2, Nr2f1, Tnfrsf1a (Tnfr1), Tnfrsf1b
Transcription Factors
Egr1, Foxp3, Hdac1, Hif1a, Myc, Nfkb1, Nr2f1, Stat3
Other Multiple Sclerosis Genes
Aspa, Edc4, Gfap, Gnai2, Grb2, Jak1, Phgdh, Rangap1, Top1, Tubb4a, Ywhah