Target List
Angiogenic Growth Factors
Edn1, Nrp2, Tpm1, Vegfa
Apoptosis
Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Bcl2l1 (Bcl-xl), Dapl1
BMP / TGFβ / Activin Signaling
Bmp2, Bmp4, Bmp7, Grem1, Nog, Wnt11
Calcium Signaling
Pkd1, Pkd2, Slc26a7, Slc2a9, Slc5a10
cAMP Signaling
Acy1, Adcy2, Adcy3, Ptger2, Ptger3, Ptgs2 (Cox2), Adcy7, Crebbp (CBP), P2rx7
Nephron Segment Differentiation
Angpt2, Apoe, Apom
Integrin Signaling
Cldn10, Clu, Col12a1, Col3a1, Fbln1, Fn1, Pcdh7, Rhoa, Itga8, Spry1
Growth Factors & Receptors
Egr3, Fgf1, Fgfr3, Igf1r, Ntrk3, Tgfb3
Immune & Inflammatory Responses
Cfd, Cxcl1, Cyp8b1, Il17d, Il6, Kng1, Nrg1 (Hgl), Pck1, Pla2g2a, Prlr, Ptprz1
mTOR Signaling
Pik3ca (p110-alpha), Pik3r1 (PI3KA)
Primary Cilia
Cys1, Ift88, Lgals3, Pdgfra, Pkhd1, Tmem27, Umod, Gli2
Transcription Factors
FosB, Jun, Gli2, Wt1, Tcf21
Other Polycystic Kidney Disease Genes
Agxt2, Aldh8a1, Clcnka, Dpep1, Hgd, Hrg, Hsd11b2, Miox, Napsa, Osr2, Prkcb, Ret, Scn5a, Zbtb16