dPCR LNA Mutation Assays

For detecting specific DNA sequence mutations related to cancer and oncogenesis

  • Duplex assay design detects mutated and wild-type sequences
  • Choice of FAM + HEX or Atto 550 + ROX fluorescent dye combinations
  • LNA-enhanced primers and probes increase assay specificity and sensitivity
  • Wet-lab tested dPCR assays available for more than 200 targets
  • Suitable for use with circulating tumor DNA, liquid biopsy, FFPE and other tissue samples
  • Intended for use with QIAcuity Probe PCR Kits

Product

Product List31 products

GeneGlobe ID: DMH0000371 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10817 Human
AA Mutation: p.R249S
Nucleotide Mutation: c.747G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000373 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 11063 Human
AA Mutation: p.M237I
Nucleotide Mutation: c.711G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000108 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10742 Human
AA Mutation: p.H193R
Nucleotide Mutation: c.578A>G
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000382 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 342245 Human
AA Mutation: p.G154V
Nucleotide Mutation: c.461G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000475 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 220778 Human
AA Mutation: p.R158H
Nucleotide Mutation: c.473G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000119 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 129857 Human
AA Mutation: p.P152L
Nucleotide Mutation: c.455C>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000131 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 99626 Human
AA Mutation: p.C238F
Nucleotide Mutation: c.713G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000090 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10733 Human
AA Mutation: p.Q192*
Nucleotide Mutation: c.574C>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000440 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10758 Human
AA Mutation: p.Y220C
Nucleotide Mutation: c.659A>G
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000362 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10714 Human
AA Mutation: p.R158L
Nucleotide Mutation: c.473G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000376 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 11218 Human
AA Mutation: p.T155N
Nucleotide Mutation: c.464C>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000112 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10808 Human
AA Mutation: p.Y163C
Nucleotide Mutation: c.488A>G
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000434 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10739 Human
AA Mutation: p.A161T
Nucleotide Mutation: c.481G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000094 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10660 Human
AA Mutation: p.R273H
Nucleotide Mutation: c.818G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000372 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10863 Human
AA Mutation: p.P278L
Nucleotide Mutation: c.833C>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000380 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 43871 Human
AA Mutation: p.R249M
Nucleotide Mutation: c.746G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000470 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 43687 Human
AA Mutation: p.H214R
Nucleotide Mutation: c.641A>G
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000375 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 11196 Human
AA Mutation: p.G245V
Nucleotide Mutation: c.734G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000120 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 131481 Human
AA Mutation: p.V157F
Nucleotide Mutation: c.469G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000448 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 6932 Human
AA Mutation: p.G245S
Nucleotide Mutation: c.733G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000381 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 6549 Human
AA Mutation: p.R248L
Nucleotide Mutation: c.743G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000364 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 1645467 Human
AA Mutation: p.E286K
Nucleotide Mutation: c.856G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000463 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 43947 Human
AA Mutation: p.Y205C
Nucleotide Mutation: c.614A>G
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000114 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 3675521 Human
AA Mutation: p.R273L
Nucleotide Mutation: c.818G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000361 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10710 Human
AA Mutation: p.E298*
Nucleotide Mutation: c.892G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000377 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 43629 Human
AA Mutation: p.R249W
Nucleotide Mutation: c.745A>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000104 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10891 Human
AA Mutation: p.V272M
Nucleotide Mutation: c.814G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000471 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10810 Human
AA Mutation: p.C242F
Nucleotide Mutation: c.725G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000353 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 10645 Human
AA Mutation: p.C176F
Nucleotide Mutation: c.527G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000374 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 11081 Human
AA Mutation: p.G245C
Nucleotide Mutation: c.733G>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000126 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay TP53 43559 Human
AA Mutation: p.V173L
Nucleotide Mutation: c.517G>T
dPCR wet-lab validated
Product Specification
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Resources

Instrument User Manuals (1)
Quick-Start Protocols (1)
Safety Data Sheets (1)
Application Notes (1)
Digital PCR (dPCR) is a powerful technique that detects and quantifies ultra-rare mutations in a high background of wild-type cfDNA down to 0.1% variant allele frequency. Here, we describe end-to-end manual and automated workflows that enable accurate detection and absolute quantification of ultra-rare PIK3CA variants in cfDNA using the QIAcuity Digital PCR System.
Certificates of Analysis (1)