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GeneGlobe ID: PHS-3200Z | Cat. No.: | QIAseq Targeted DNA Pro Panels

QIAseq Targeted DNA Pro Human Comprehensive Hereditary Cancer Research Panel

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Product Specification

Kit containing ALL reagents (except indexes) for targeted DNA sequencing

Target List

Covers all exons in all known transcripts of targeted genes based on the Human GRCh38 genome build

Central Nervous System Cancers
Anaplastic Glial Tumors​
CDKN2ACDKN2BPTENRB1TP53
Astrocytomas​
APCATRXBRAFCDKN2ACDKN2BCDKN2B-AS1CHEK2FGFR1HIPK2HRASIDH1MSH2MYBNF1PALB2PTPN11RB1SDHATP53TSC1
Atypical Teratoid Rhabdoid Tumors​
SMARCA4SMARCB1
Craniopharyngiomas​
BRAFCTNNB1
Ependymomas​
CDKN2AERBB2MEN1NF2TP53
Ganglioneuromas​
ALKPHOX2B
Glioblastomas​
ALKAPCBCORBRAFBRCA2CDK4CDKN2ACDKN2BCREBBPEGFREPCAMERBB2IDH1KITLZTR1MLH1MSH2MSH6MTORMYCNRASPIK3CAPMS2PTENRB1TP53
Gliomas​
ACVR1ADGRB3ATRXBRAFBRCA2BRIP1CDKN2ACHD2CHEK2CICEGFREP300FGFR1FLT1H3-3AIDH1IRS2MDM4MYBMYCNNF1NSD2PDGFRAPIK3CAPOT1PTENSTYK1TP53
Hereditary Paraganglioma-Pheochromocytoma Syndrome​
MAXSDHAF2SDHBSDHCSDHDTMEM127
Intercranial Ependymomas​
CDKN2ACDKN2B
Lynch Syndrome​
EPCAMMLH1MSH2MSH6PMS2
Medulloblastomas​
ALPK2APCBRCA2CACNA1DCDH1CDK4CHD7CLTCL1CREBBPCTCFCTNNB1DDX3XDDX60DEPDC5DICER1DNAH14DYNC1H1ERBB2FAPFCRL2FGFR1GABRG1GPAMHDAC9IDH1IFIT3IRX2KAT6AKDM4CKDM6AKIF7KMT2BKMT2DLRRK1LRRK2MAST4MSH2MYCMYCNNCAPD3NLRP5NRASNRP1OTOFOTX2PARP2PCDHGB3PFKPPIK3CAPRKAG2PRLRPTCH1PTCH2PTENRAB11FIP1RB1SF3B1SMARCA4SMARCB1SUFUTP53TPOTTNWDFY3WDFY4WRNZMYM3
Meningiomas​
CDKN2ACDKN2BG6PDMN1NF2PDGFBPTENSMARCE1SUFU
Neuroblastomas​
ALKBRCA1BRCA2DICER1EZH2HRASKIF1BNRASPHOX2BPTCH1PTPN11SMARCA4TP53
Neurofibromas​
EPCAMMLH1MSH2MSH6NF1PMS2
Neurofibromatosis​
NF1NF2
Oligodendrogliomas​
CDKN2ACDKN2BIDH1MSH2RB1
Tuberous Sclerosis Complex​
TSC1TSC2
Other Central Nervous System Cancer Genes​
AIPCDKN1BEPHB2PRKAR1AVHL
Colorectal Cancers
Adenocarcinomas​
APCATMAXIN2BMPR1ABRAFBRCA1BRCA2CHEK2EP300FLCNMLH1MLH3MSH2MSH3MSH6MUTYHNRASPALB2PMS1PMS2POLD1POLEPTENRNF43SMAD4STK11TGFBR2TP53
Colorectal Cancer Susceptibility​
CCND1GALNT12POLD1POLESMAD7
Familial Adenomatous Polyposis​
APCMSH3MUTYHNTHL1POLD1POLE
Hereditary Mixed Polyposis Syndrome​
BMPR1AGREM1
Hereditary Nonpolyposis​
BRAFEPCAMMLH1MLH3MSH2MSH6PMS1PMS2TGFBR2
Hereditary Polyposis Syndrome​
BMPR1AGREM1
Juvenile Polyposis Syndrome​
BMPR1ASMAD4
Lynch Syndrome​
BRAFEPCAMMLH1MLH3MSH2MSH6PMS1PMS2TGFBR2
Metastatic Colorectal Cancers​
ATMBRAFNRAS
Muir-Torre Syndrome​
MLH1MSH2
Other Colorectal Cancer Genes​
AURKABLMCDH1PKHD1PLA2G2ARB1RPS20SEMA4ATLR2XRCC2
Gastric Cancers
Gastrointestinal Stromal Tumors (GIST)​
KITNF1PDGFRASDHBSDHCSDHDTMEM127
Lynch Syndrome​
EPCAMMLH1MSH2MSH6PMS2
Multiple Endocrine Neoplasia​
CDKN1BMEN1
Other Gastric Cancer Genes​
APCATMBMPR1ACDH1CHEK2CTNNA1KRASSMAD4STK11TP53
Hematological Malignancies
Eosinophilia​
CR2JAK1
Lymphoproliferative Disorders​
PLAASH2D1AXIAP
Mastocytosis​
DNMT3AIDH2KITNRASRUNX1
Multiple Myeloma​
ATMCCND1IDH1IDH2KITLIG4NRASTP53
Myelodysplastic Syndromes​
CEBPADNMT3AGATA2GNB1IDH1IDH2KITMPLMSH6NF1NRASRUNX1SMAD9TERCTERTTP53
Myelofibrosis​
DNMT3AIDH1IDH2MPLNF1NRASTP53
Myeloproliferative Neoplasms​
DNMT3AIDH1IDH2MPLRUNX1SH2B3TP53
Polycythemia Vera​
DNMT3AIDH1NRASTP53
Thrombocythemia​
IDH2MPLSH2B3THPOTP53
Other Hematological Malignancies Genes​
BLMEPCAMHRASMLH1MSH2NBNPMS2
Hereditary Breast & Ovarian Cancers (HBOC)
Familial Breast-Ovarian Cancer Susceptibility​
BRCA1BRCA2FGFR2MAP3K1RAD51CRAD51DTOX3
Breast Cancer Carcinomas​
ATMBARD1BRCA1BRCA2BRIP1CHEK2ERBB2ESR1MLH1MSH2MSH6PALB2PIK3CAPMS2RAD51CRAD51D
Breast Cancer Ductal Carcinomas​
CDH1FGFR2MRE11NBNSTK11TP53
Breast Cancer Susceptibility​
BARD1BRCA2PALB2RECQLXRCC3
Metastatic Breast Cancers​
BRCA1BRCA2ERBB2ESR1NF1PALB2PIK3CAPTEN
Other Breast Cancer Genes​
APCAXIN2SDHBSMARCA4TSHR
Ovarian Cancer Epithelial Carcinomas​
ABRAXAS1ATMBARD1BRCA1BRCA2BRIP1CHEK2ERBB2MRE11NBNNF1PALB2PIK3CAPTENRAD51CRAD51DTP53
Ovarian Cancer Mixed Adenosquamous Carcinomas​
BLMCDH1DICER1FANCCFANCMFGFR2RAD50RAD51SMARCA4STK11
Other Ovarian Cancer Genes​
MLH1RECQLRINT1XRCC2
Uterine Serous Carcinomas​
BLMCDH1DICER1FANCCFANCMFGFR2RAD50RAD51SMARCA4
Lynch Syndrome​
EPCAMMLH1MSH2MSH6PMS2
Other Hereditary Breast & Ovarian Cancer Genes​
HMMRMUTYHNQO2PGRPHBPOLD1PRKAR1A
Kidney Cancers
Hamartomas​
CDC73DIS3L2
Lynch Syndrome​
EPCAMMLH1MSH6PMS2
Nephroblastomas​
CDKN1CDIS3L2TRIM28
Papillary Renal Cell Carcinomas​
FHMET
Renal Cell Carcinomas​
BAP1BRAFFGFR3FHFLCNHNF1AHNF1BMETMITFMSH2MTORNRASPIK3CAPTENSDHASDHBSDHCSDHDTMEM127TP53VHL
Rhabdoid Tumors​
SMARCA4SMARCB1
Tuberous Sclerosis Complex​
TSC1TSC2
Wilms Tumors​
BRAFBRCA2CDC73CDKN1CDICER1DIS3L2FZD6GPC3PAX6RESTVHLWT1
Other Kidney Cancer Genes​
BUB1B
Myeloid Neoplasms
Acute Lymphoblastic Leukemia (ALL)​
BRAFCDKN2ACDKN2BCREBBPEP300ETV6EZH2FBXW7FLT3GATA3H2AC7H2BC6H2BC7H3C4H4C4IKZF1IKZF2IKZF3IL7RJAK1JAK2JAK3KRASMAPK1NF1NOTCH1NRASPAG1PAX5PTENPTPN11RB1RUNX1SH2B3TP53
Acute Megakaryoblastic Leukemia (AMKL)​
ERGGATA1JAK2METMPLOLIG2RUNX1SMOTMPRSS2
Acute Myeloid Leukemia (AML)​
BRCA2CEBPACHIC2DDX41DNMT3AETV6FLT3GATA1GATA2IDH1IDH2IKZF1IKZF2IKZF3JAK2KITKRASLPPMLLT10NRASPTPN11RB1RUNX1SH3GL1TERTTP53WT1
Acute Promyelocytic Leukemia (APML; APL)​
CEBPARUNX1
Atypical Chronic Myeloid Leukemia (aCML)​
CBLCEBPAEZH2FLT3JAK2KRASNRASRUNX1SETBP1
B Cell Acute Lymphoblastic Leukemia (B-ALL)​
IKZF1JAK1JAK2PAX5
Chronic Lymphocytic Leukemia (CLL)​
BRAFGNB1NOTCH1NRASPTPN11TP53
Chronic Myeloid Leukemia (CML)​
BRAFCBLCREBBPDNMT3AEZH2IDH1IDH2IKZF1JAK2KRASNRASRUNX1TP53WT1
Chronic Myelomonocytic Leukemia (CMML)​
CBLCEBPADNMT3AEZH2FLT3IDH1IDH2JAK2KITKRASMPLNF1NRASPHF6PTPN11RUNX1SETBP1TP53
Early T-Cell Precursor Acute Lymphoblastic Leukemia​
BCL11BBRAFCDKN2ACDKN2BCTCFDCLRE1CDNM2ECT2LEEDEP300ETV6EZH2FBXW7FLT3GATA2GATA3H1-5HNRNPA1HNRNPRIKZF1IL7RJAK1JAK3KRASLEF1LMO2MYBNF1NOTCH1NRASPHF6PTENPTPN11RB1RELNRUNX1SETD2SH2B3SUZ12TAL1WT1
Hairy Cell Leukemia​
BRAFTP53
Juvenile Myelomonocytic Leukemia​
CBLKRASNF1NRASPTPN11
T Cell Acute Lymphoblastic Leukemia (T-ALL)​
FBXW7NOTCH1
Other Leukemia Genes​
APCATMCDH1DICER1DNAJC21ERBB3ERCC2ERCC4KCNQ1MSH2MSH6MUTYHNBNNSD1RECQL4RETSOS1STK11TSC2
Acute Lymphoblastic Lymphomas​
CDKN2ACDKN2BNOTCH1TP53
B Cell Lymphomas​
BRAFCHEK2EZH2TP53
Follicular Lymphomas​
CREBBPEP300EZH2
Non-Hodgkin Lymphomas​
BRAFNRASPIK3CATP53
T Cell Lymphomas​
ATMDNMT3AHAVCR2IDH1IDH2JAK1JAK3SETD2
Other Lymphoma Genes​
B2MBRCA2CEBPAKITKLHDC8BMSH2MSH6MUTYHPRF1PTPN11RB1RECQL4RETSTK11TSC2
Myelodysplastic Syndromes​
CBLCEBPADDX41DNMT3AETV6EZH2FLT3GATA2GNB1IDH1IDH2JAK2JAK3KITKRASMPLNF1NRASPHF6PTPN11RUNX1SETBP1TERCTERTTP53WT1
Myeloproliferative Neoplasms​
CBLDNMT3AEZH2IDH1IDH2JAK2MPLRUNX1SH2B3TP53
Essential Thrombocythemia​
CBLIDH2JAK2MPLTP53
Fanconi Anemia​
FANCAFANCBFANCD2FANCEFANCFFANCGFANCIFANCMSLX4
Mastocytosis​
CBLEZH2IDH2JAK2KITKRASNRASRUNX1
Multiple Myeloma​
ATMBRAFBRCA2CHEK2FANCLIDH1IDH2KITKRASMETNRASRETTP53
Polycythemia Vera​
DNMT3AEZH2IDH1JAK2NRASTP53
Primary Myelofibrosis​
CBLDNMT3AEZH2IDH1IDH2JAK2MPLNF1NRASSETBP1TP53
Systemic Mastocytosis​
CBLDNMT3AETV6EZH2IDH2JAK2KITKRASNRASRUNX1SETBP1
Pancreatic Cancers
Adenocarcinomas​
ATMBRCA1BRCA2CDKN2ACFTREPCAMFANCCMLH1MSH2MSH6PALB2PALLDPMS2PRSS1SMAD4SPINK1STK11TP53
Adenomas​
TSC1TSC2
Familial Pancreatic Cancers​
ATMBRCA2CDKN2APALB2
Hereditary Pancreatitis​
CFTRCTRCPRSS1PRSS2SPINK1
Lynch Syndrome​
EPCAMMLH1MSH2MSH6PMS2
Multiple Endocrine Neoplasia​
CDKN1BMEN1
Pancreatic Cancer Susceptibility​
BRCA1BRCA2PALB2PALLDRABL3
Other Pancreatic Cancer Genes​
APCBMPR1ACASRCDK4CPA1NF1VHL
Pediatric Cancers
Craniopharyngiomas​
APCSMARCA4SUFUTSC1
Embryonal Rhabdomyosarcomas​
CARD11CTNNB1FGFR4HRASKRASMDM2MDM4NF1NRASPIK3CARARATP53
Ependymomas​
MEN1NF2
Ewing's Sarcoma​
NF1RET
Germ Cell Tumors​
BRAFCBLFANCMPTEN
Hepatoblastomas​
CDK4MSH6TP53
Hepatocellular Carcinomas​
APCCREBBPCTNNB1IDH1KRASMETNRASPIK3CATERTTP53
Lynch Syndrome​
EPCAMMLH1PMS2
Nephroblastomas​
BRCA2CDKN1CDIS3L2PAX6POU6F2RESTSMARCB1WT1
Neuroblastomas​
ALKPHOX2BPTCH1
Osteosarcomas​
ATRXCDKN2ACHEK2RB1RECQL4TP53TSC2
Retinoblastomas​
APCCEBPAMAXRB1STK11TSC2
Rhabdomyosarcomas​
BRCA1DICER1FOXO1MSH2PAX3PAX7
Other Pediatric Cancer Genes​
CDC73PRKAR1AVHL
Prostate Cancers
Adenocarcinomas​
ARBRIP1CHEK2NBNPTENRAD51CRAD51DTP53
Advanced Prostate Cancers​
ATMBRCA1BRCA2PALB2PTEN
Lynch Syndrome​
EPCAMMLH1MSH2MSH6PMS2
Other Prostate Cancer Genes​
CDH1EHBP1ELAC2HOXB13MSMBRNASEL
Skin Cancers
Cutaneous Melanomas​
BAP1CDK4CDKN2AMC1RMITFPOT1XRCC3
Malignant Melanoma Susceptibility​
CDK4CDKN2AMC1RMITFPOT1TERTXRCC3
Malignant Melanomas​
CDK4CDKN2AMC1RMITFPOT1XRCC3
Melanomas​
BRAFBRCA1BRCA2CDK4CDKN2ACDKN2B-AS1CREBBPIDH1KITKRASMAP2K1MAP2K2MC1RMITFNRASPIK3CAPOT1PTENRAF1RB1TERTTP53TYR
Uveal Melanomas​
BAP1BRCA2CDKN2ACDKN2B
Xeroderma Pigmentosum​
DDB2ERCC2ERCC3ERCC4ERCC5POLHXPAXPC
Other Skin Cancer Genes​
ATRCYLDFHFLCNPRKAR1APTCH2

Product Resources

icon_0041_download-s Download Target List

Resources

Application Notes (3)
BeckmanCoulter QIAseq DNA Pro Panels Biomek i7
PDF (1MB)
Automation of the QIAseq Targeted DNA Pro Panel Method on the HAMILTON NGS STAR V
PDF (1MB)
Automation of the QIAGEN QIAseq Targeted DNA Pro Panels on the Hamilton NGS STAR MOA
PDF (694KB)
Brochures & Guides (1)
QIAseq Targeted DNA Pro Panel Go Greener Fact Sheet
PDF (95KB)
This fact sheet explains the inclusion of QIAseq Targeted DNA Pro Panels in our Go Greener program.
Kit Handbooks (2)
QIAseq Targeted DNA Pro Handbook for Illumina
PDF (976KB)
For ultrasensitive targeted next-generation sequencing (NGS) of DNA for Illumina NGS systems
QIAseq Targeted DNA Pro Handbook for Thermo
PDF (1MB)
For ultrasensitive targeted next-generation sequencing of DNA for Ion Torrent NGS systems
Technical Information and Important Notes (1)
A Sample to Insight NGS solution for myeloid neoplasms: Redefined amplicon sequencing for low-variant detection and interpretation
PDF (2MB)
Template Files (1)
QIAseq Targeted DNA Pro Template File
ZIP (212KB)
Safety Data Sheets (1)
Safety Data Sheets
Certificates of Analysis (1)
Certificates of Analysis
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Introducing the QIAseq Targeted DNA Pro Human Comprehensive Hereditary Cancer Research Panel, a cutting-edge addition to our QIAseq Targeted DNA Pro Panels lineup, specifically designed for NGS applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the QIAseq Targeted DNA Pro Human Comprehensive Hereditary Cancer Research Panel facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting NGS, or any other sophisticated analyses, this product from our QIAseq Targeted DNA Pro Panels collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with QIAseq Targeted DNA Pro Human Comprehensive Hereditary Cancer Research Panel and elevate your work to new heights.
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