dPCR LNA Mutation Assays

For detecting specific DNA sequence mutations related to cancer and oncogenesis

  • Duplex assay design detects mutated and wild-type sequences
  • Choice of FAM + HEX or Atto 550 + ROX fluorescent dye combinations
  • LNA-enhanced primers and probes increase assay specificity and sensitivity
  • Wet-lab tested dPCR assays available for more than 200 targets
  • Suitable for use with circulating tumor DNA, liquid biopsy, FFPE and other tissue samples
  • Intended for use with QIAcuity Probe PCR Kits

Product

Product List8 products

GeneGlobe ID: DMH0000148 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay NOTCH1 4775081 Human
AA Mutation: p.I1616N
Nucleotide Mutation: c.4847T>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000136 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay NOTCH1 13050 Human
AA Mutation: p.F1592S
Nucleotide Mutation: c.4775T>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000146 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay NOTCH1 13053 Human
AA Mutation: p.R1598P
Nucleotide Mutation: c.4793G>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000487 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay NOTCH1 1624742 Human
AA Mutation: p.T194P
Nucleotide Mutation: c.580A>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000486 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay NOTCH1 4590155 Human
AA Mutation: p.D573A
Nucleotide Mutation: c.1718A>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000144 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay NOTCH1 4163569 Human
AA Mutation: p.T311P
Nucleotide Mutation: c.931A>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000027 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay NOTCH1 13048 Human
AA Mutation: p.L1678P
Nucleotide Mutation: c.5033T>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000026 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay NOTCH1 12774 Human
AA Mutation: p.P2514Rfs*4
Nucleotide Mutation: c.7541_7542del
dPCR wet-lab validated
Product Specification
You've viewed 5 of 8 Products
Load more products

Resources

Instrument User Manuals (1)
Quick-Start Protocols (1)
Safety Data Sheets (1)
Application Notes (1)
Digital PCR (dPCR) is a powerful technique that detects and quantifies ultra-rare mutations in a high background of wild-type cfDNA down to 0.1% variant allele frequency. Here, we describe end-to-end manual and automated workflows that enable accurate detection and absolute quantification of ultra-rare PIK3CA variants in cfDNA using the QIAcuity Digital PCR System.
Certificates of Analysis (1)