3'-5'-cyclic adenosine monophosphate (cAMP) is a second messenger central to a number of biological processes. It is produced by the catalytic action of adenylyl cylcase (AC) on ATP. AC activity is regulated via its interaction with activating (Gαs) or inhibiting (Gαi) G-proteins.PKA is an important target of cAMP activation. PKA consisting of a catalytic and a regulatory subunit...