Target List
Growth Factors & Receptors
FLT1 (VEGFR1), FLT4 (VEGFR2), KDR (VEGFR3), NRP1, NRP2, PDGFC, PGF, VEGFA, VEGFB, VEGFC, VEGFD (VEGFD)
AKT & PI3 Kinase Signaling
AKT1, AKT2, AKT3, PIK3CA (p110-alpha), PIK3CB, PIK3CD, PIK3CG, PIK3R1 (p85-ALPHA), PIK3R2 (p85-BETA), PIK3R3, PIK3R5
Small G-Protein Signaling
HRAS, KRAS, NRAS, RAC1, RAC2, RAF1, SHC2, SRC
Heat Shock Proteins
HSP90AA1, HSPB1 (HSP27)
MAP Kinase Signaling
MAP2K1, MAP2K2 (MEK2), MAPK1 (ERK2), MAPK11 (p38Beta), MAPK12 (p38GAMMA), MAPK13 (p38delta), MAPK14 (p38ALPHA), MAPK3 (ERK1), MAPKAPK2, MAPKAPK3
NFAT Signaling
NFAT5, NFATC1, NFATC2, NFATC3, NFATC4 (NFAT3)
Phospholipases
PLA2G10, PLA2G12A, PLA2G12B, PLA2G1B, PLA2G2A, PLA2G2D, PLA2G2E, PLA2G2F, PLA2G3, PLA2G4A, PLA2G4B, PLA2G5, PLA2G6, PLCG1, PLCG2
Protein Kinase C
PRKCA, PRKCB, PRKCG
Protein Phosphatases
PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2
Transcription Factors
ARNT, HIF1A, NFAT5, NFATC1, NFATC2, NFATC3, NFATC4 (NFAT3)
Apoptosis & Cell Cycle
BAD, CASP9, CDC42
Cell Migration & Morphology
PTK2 (FAK), PXN
Other VEGF Signaling Genes
CAV1, GRB2, NOS3 (eNOS), PTGS2 (COX2), SH2D2A, SPHK1, SPHK2