GeneGlobe ID: UPHS-156Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels

QuantiNova LNA Probe PCR Focus Panel Human Insulin Resistance

QuantiNova LNA Probe PCR Focus Panel

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Product Specification

Target List

Insulin Signaling
AKT3, IGF1, IGF1R, IKBKB (IKKβ), INSR, IRS1, IRS2, MAP2K1, MAPK3 (ERK1), MAPK9 (JNK2), MTOR, PDE3B, PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), PPARGC1A (PGC-1α), PTPN1 (PTP1B), RPS6KB1, SLC2A4 (GLUT4), SOCS3, SREBF1
Non-Insulin Dependent Diabetes Mellitus
ADIPOQ (ACRP30), HK2, IKBKB (IKKβ), INSR, IRS1, IRS2, MAPK3 (ERK1), MAPK9 (JNK2), MTOR, PDX1, PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), SLC2A4 (GLUT4), SOCS3, TNF
Adipokine Signaling
Adipokines​
ADIPOQ (ACRP30), IL6, LEP (Leptin), NAMPT, RETN, SERPINE1 (PAI-1), TNF
Receptors & Transporters​
ADIPOR1, ADIPOR2, CD36, LEPR, SLC2A4 (GLUT4), TNFRSF1A (TNFR1), TNFRSF1B
Signaling Downstream of Adipokines​
AKT3, CHUK (IKKα), IKBKB (IKKβ), IRS1, IRS2, JAK2, MAPK9 (JNK2), MTOR, NFKBIA (IκBα, MAD3), PPARA, PPARGC1A (PGC-1α), RELA, SOCS3, STAT3
Innate Immunity
CASP1 (ICE), CHUK (IKKα), IKBKB (IKKβ), IRS1, IRS2, NLRP3, NFKBIA (IκBα, MAD3), PYCARD (TMS1, ASC), RELA, TLR4
Inflammation
ALOX5, CASP1 (ICE), CCL2 (MCP-1), CCR4, CCR5, CHUK (IKKα), CXCR4, IFNG, IKBKB (IKKβ), IL1B, IL23R, IL6, CXCL8 (IL8), LTA4H, NLRP3, OLR1, PYCARD (TMS1, ASC), RELA, TNF, TNFRSF1A (TNFR1), TNFRSF1B
Apoptosis
PPARG, SERPINE1 (PAI-1), TNF, CASP1 (ICE), IKBKB (IKKβ), IRS2, MAPK9 (JNK2), NFKBIA (IκBα, MAD3), NLRP3, PYCARD (TMS1, ASC), RELA, TNFRSF1A (TNFR1), JAK2, PIK3CA (p110-alpha), SOCS3, RPS6KB1, TNFRSF1B
Metabolic Pathways
Carbohydrate Metabolism​
CS, HK2, PCK1, PDK2
Lipid Metabolism​
ACACA, ACACB, ACSL1, ACSL4, APOE, CEBPA, CNBP, FABP4, FASN, LEPR, LIPE, LPL, PPARA, PPARG, PPARGC1A (PGC-1α), SCD, SREBF1, SREBF2
Metabolite Transport​
APOE, CD36, FABP4, RBP4, SLC2A4 (GLUT4), SLC27A1, UCP1, VLDLR
Infiltrating Leukocyte Markers
Macrophages​
CCR5, CXCR4, ADGRE1 (EMR1)
Th1 Cells​
CCR5, CD3E, CXCR3, IL18R1
Th2 Cells​
CCR4, CD3E, CRLF2 (TSLPR), IL1R1
Th17 Cells​
CCR6, CD3E, IL23R

Product Resources

Array Layout for PCR Plates
File Size: 153.58 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 153.72 KBLanguage: English

Resources

Kit Handbooks (1)
QuantiNova LNA Probe PCR Handbook
Quick-Start Protocols (1)
Safety Data Sheets (1)
Certificates of Analysis (1)
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