GeneGlobe ID: PAHS-093Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays

RT² Profiler™ PCR Array Human Hepatoxicity

RT2 Profiler PCR Array

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Product Specification

Target List

Cholestasis
ABCB1 (MDR1, PGY1), ABCB4, ABCC2 (MRP2, cMOAT), ABCC3 (MRP3, MOAT-D), ATP8B1, ICAM1, SLC51A, PDYN, RDX
Steatosis
Up-Regulated in Steatosis​
CD36, FASN, LPL, SCD
Down-Regulated in Steatosis​
PPARA, SREBF1
Phospholipidosis
Up-Regulated in Phospholipidosis​
ASAH1, FABP1, HPN, LSS, MRPS18B, S100A8, SERPINA3, WIPI1
Down-Regulated in Phospholipidosis​
SLC2A3, TAGLN
Regulated in Phospholipidosis​
ABCB1 (MDR1, PGY1), TIMM10B
Hepatotoxicity
Up-Regulated in Hepatotoxicity​
ALDOA, APEX1, BTG2, CASP3, CCNG1, CRYL1, DDIT4L (REDD2), DNAJB11, DNAJC3, GADD45A, GCLC, GSR, HMOX1, HYOU1, KRT18, KRT8, NQO1, PLA2G12A, SLC17A3, TXNRD1, YRDC
Down-Regulated in Hepatotoxicity​
AVPR1A, BHMT, CA3, CXCL12 (SDF1), CYP1A2, FADS1, FMO1, HAO2, IGFALS, MBL2, RB1, THRSP
Regulated in Hepatotoxicity​
ABCB11, TIMM10B, MAOB, PYGL
Nongenotoxic Hepatocarcinogenicity
Up-Regulated in Nongenotoxic Hepatocarcinogenicity​
ALDOA, APEX1, BTG2, CCNG1, CDKN1A (p21CIP1, WAF1), DDX39A, KRT8, KRT18, MRPS18B, TXNRD1
Necrosis
Up-Regulated in Necrosis​
CD68, COL4A1, IL6ST (GP130), IPO4, MAP3K6, NUS1, OSMR, PSME3, SERPINE1 (PAI-1), SKIL, SLC39A6, CEMIP2
Down-Regulated in Necrosis​
CDC14B, EMC9, FAM214A, L2HGDH, LGR5, MCM10, MLXIPL, RHBG
Regulated in Necrosis​
CDKN1A (p21CIP1, WAF1), DDX39A

Product Resources

Array Layout for PCR Plates
File Size: 139.04 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 132.71 KBLanguage: English

Resources

Brochures & Guides (3)
Simultaneously profile mRNA, miRNA and lncRNA using a simple, complete workflow
Safety Data Sheets (1)
Download Files (3)
For analyzing gene expression data from RT2 Profiler PCR Arrays 
Data analysis file for RT² Profiler PCR Array Housekeeping Genes
Catalog number- 330231
Pathway number- PAXX-000
RNA QC Data Analysis
XLS (484KB)

Data analysis file for RT² ProfilerRT² Profiler™ PCR Array RT2 RNA QC
Catalog number- 330231
Pathway number- PAXX-999

Scientific Posters (1)
Poster for download
Kit Handbooks (1)
For pathway-focused gene expression profiling using real-time RT-PCR
Instrument Technical Documents (2)
For gene expression and genomic analysis
For pathway-focused gene expression analysis
Certificates of Analysis (1)
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Introducing the RT² Profiler™ PCR Array Human Hepatoxicity, a cutting-edge addition to our RT2 Profiler PCR Arrays lineup, specifically designed for Real-Time PCR applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the RT² Profiler™ PCR Array Human Hepatoxicity facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting Real-Time PCR, or any other sophisticated analyses, this product from our RT2 Profiler PCR Arrays collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with RT² Profiler™ PCR Array Human Hepatoxicity and elevate your work to new heights.