Target List
Conduction of Pain
Ion Channels
TRPA1, LOC100515051
Sodium Channels
LOC100739142, SCN9A, SLC6A2
Potassium Channels
KCNIP3, KCNJ6, KCNJ10, KCNQ3, KCNK2
Purinergic (P2Y) Receptors
P2RX4, ADORA1, P2RX3, P2RX7, P2RY1
Opioid Receptors
OPRD1, OPRK1, OPRM1
Cannabinoid Receptors
CNR1, CNR2
Synaptic Transmission
Glutamate Receptors
GRIN1, GRIN2B, GRIN2D, GRM1, LOC100622280
Serotonin (5-Hydroxytryptamine) Receptors
HTR2A
Pain Response Modulation
Eicosanoid Metabolism
PTGER2 (EP2), PLA2G1B, PTGER3, PTGES, PTGES2, PTGS1, PTGS2 (PGHS-2, COX2)
Inflammation
ACE, ALOX5, BDKRB2, CCK, CCL2 (MCP-1), CCR2, CD14, CD4, CHRNB2, CSF1 (MCSF), DBH, EDN1, EDNRA, F2R (PAR1), FAAH, IL10, IL18, IL1A, IL1B, IL2, IL6, LOC397459, ITGB2, LIF, OSM, PRKCG, CX3CR1, LOC100622645 (GCH1), CCKBR, CD200, MAPK1 (ERK2), MAPK1 (ERK2), MAPK14 (p38ALPHA), MAPK14 (p38ALPHA), MAPK3 (ERK1), MAPK3 (ERK1), MAPK8, NOS2, PENK, PNOC, RTN4, TLR2, TLR4, TNF, TSPO (BZRP)
Neurotransmitters
ADRB1, ADRB2, COMT, DBH, MAOB, NPVF, PDYN, PENK, PNOC
Neurotrophins
BDNF, GDNF, NTRK1