Hectd2 Gene Summary [Rat]
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination. Orthologous to human HECTD2 (HECT domain E3 ubiquitin protein ligase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hectd2 |
| Official Name | HECT domain E3 ubiquitin protein ligase 2 [Source:RGD Symbol;Acc:1305536] |
| Ensembl ID | ENSRNOG00000056753 |
| Bio databases IDs | |
| Aliases | HECT domain E3 ubiquitin protein ligase 2 |
| Synonyms | 4921524L07, A630025O09Rik, HECT domain E3 ubiquitin protein ligase 2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Hectd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- HECTc
- Domain Homologous to E6-AP Carboxyl Terminus with
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Hectd2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein polyubiquitination
Cellular Component
Where in the cell the gene product is active
- cytosol