Wnt glycolipoproteins are extracellular ligands that can be found in many species, ranging from the sea anemone to human. Wnts are signaling factors regulating several key developmental processes, such as proliferation, differentiation, asymmetric division, patterning and cell fate determination.The non-canonical Wnt/Ca2+ signaling cascade is less characterized than their canonical counterpart, the Wnt/β-catenin pathway. The Wnt/Ca2+ signaling pathway was deciphered as a crucial mediator in development. However, now there is substantial evidence that the signaling cascade is involved in many other molecular phenomena...