dPCR LNA Mutation Assays

用于检测与癌症和肿瘤发生有关的特定 DNA 序列突变

  • 双重检测设计,可检测突变型及野生型序列
  • 可选 FAM + HEX 或 Atto 550 + ROX 荧光探针染料组合
  • LNA 加持的引物和探针,可提高检测的特异性和灵敏度
  • 经过湿实验验证的 dPCR 检测,有 200 多个靶标基因可供选择
  • 适用于循环肿瘤 DNA、液体活检、FFPE 和其他组织样本
  • 旨在搭配 QIAcuity Probe PCR Kit 一起使用

Product

Product List4 products

GeneGlobe ID: DMH0000571 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay ABL1 12576 Human
AA Mutation: p.Y272H
Nucleotide Mutation: c.814T>C
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000306 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay ABL1 12560 Human
AA Mutation: p.T334I
Nucleotide Mutation: c.1001C>T
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000573 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay ABL1 12573 Human
AA Mutation: p.E274K
Nucleotide Mutation: c.820G>A
dPCR wet-lab validated
Product Specification
GeneGlobe ID: DMH0000053 | Cat. No.: | dPCR LNA Mutation Assays
dPCR Mutation Assay ABL1 12574 Human
AA Mutation: p.E274V
Nucleotide Mutation: c.821A>T
dPCR wet-lab validated
Product Specification
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用户使用手册 (1)
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Download Safety Data Sheets for QIAGEN product components.
应用说明 (1)
Digital PCR (dPCR) is a powerful technique that detects and quantifies ultra-rare mutations in a high background of wild-type cfDNA down to 0.1% variant allele frequency. Here, we describe end-to-end manual and automated workflows that enable accurate detection and absolute quantification of ultra-rare PIK3CA variants in cfDNA using the QIAcuity Digital PCR System.
Safety Data Sheets (1)
Certificates of Analysis (1)
Application Notes (1)
Digital PCR (dPCR) is a powerful technique that detects and quantifies ultra-rare mutations in a high background of wild-type cfDNA down to 0.1% variant allele frequency. Here, we describe end-to-end manual and automated workflows that enable accurate detection and absolute quantification of ultra-rare PIK3CA variants in cfDNA using the QIAcuity Digital PCR System.
Quick-Start Protocols (1)
Instrument User Manuals (1)