Target List
Th2 Cytokines & Related Genes
AREG, CCL11 (Eotaxin), CCL17 (TARC), CCL2 (MCP-1), CCL22 (MDC), CCL24 (MPIF-2, Eotaxin-2), CCL26 (Eotaxin-3), CCL5 (RANTES), CCL8 (MCP-2), CLC, CSF2 (GM-CSF), PTGDR2 (CRTH2, GPR44), ICOS, IFNG, IL10, IL12A, IL12B, IL13, IL17A, IL18, IL21, IL25, IL3, IL31, IL33, IL4, IL5, IL9, PDCD1 (PD1), PDCD1 (PD1), PMCH, TGFB1, TNFSF4 (OX40L), TSLP
Cytokine & Chemokine Receptors
CCR3, CCR4, CCR8, CD40LG, CRLF2 (TSLPR), CSF3R (GM-CSFR), IFNGR2, IL13RA1, IL13RA2, IL17RB, IL1RL1 (ST2), IL2RA (CD25), IL3RA, IL4R (CD124), IL5RA (CD125), TNFRSF4 (OX40)
Transcription Factors
BCL6, FOXP3, GATA3, MAF, PPARG, RORC, SATB1, STAT5A, STAT6, TBX21
Mast Cells & IgE
CMA1, CPA3, FCER1A, KIT (CD117), KITLG (SCF), KITLG (SCF), MS4A2, TPSAB1
Eosinophils
EPX, PRG2, RNASE2, RNASE3, SIGLEC8
Natural Killer (NK) Cells
IFNG, IL12A, IL12B, IL13, IL18, IL21, IL33
Alternatively Activated Macrophages
ARG1, CHI3L1, CHIA, MRC1, RETNLB
Asthma
ADAM33, ADRB2, ALOX5, CLCA1, CYSLTR1, LTB4R, MMP9, POSTN