PLAAT5 Gene Summary [Human]
Enables N-acyltransferase activity; phospholipase A1 activity; and phospholipase A2 activity. Acts upstream of or within N-acylphosphatidylethanolamine metabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | PLAAT5 |
| Official Name | phospholipase A and acyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:24978] |
| Ensembl ID | ENSG00000168004 |
| Bio databases IDs | |
| Aliases | phospholipase A and acyltransferase 5, Ca(2+)-independent N-acyltransferase, H-rev107-like protein 5, phospholipase A/acyltransferase‐5 |
| Synonyms | 1700055A14Rik, 1700086E08Rik, 4921526K24Rik, HRASLS5, HRLP5, HRSL5, iNAT, phospholipase A and acyltransferase 5, RGD1308376, RLP-1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PLAAT5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phospholipase A1
- N-acyltransferase
- NlpC/P60 family
- enzyme
- protein binding
- phospholipase A2
Pathways
Biological processes and signaling networks where the PLAAT5 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PLAAT5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- N-acylphosphatidylethanolamine metabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- phospholipase A2 activity
- 1-acyl-2-lysophosphatidylserine acylhydrolase activity
- phosphatidylserine 1-acylhydrolase activity
- phosphatidylcholine 1-acylhydrolase activity
- N-acyltransferase activity