Target List
LDL Receptors & Associated Proteins
LDL Receptors
CXCL16, LDLR, LRP10, LRP12, LRP1B, LRP6, OLR1, STAB1, STAB2, VLDLR
LDL Receptor Associated Proteins
LRPAP1, PCSK9, SNX17
LDL Associated Proteins
ANKRA2, APOA4, APOC3, CDH13, COLEC12, SCARF1, SORL1
HDL Associated Proteins
APOA1, APOD, APOF, APOL2, APOL5
Cholesterol Transport
Cholesterol Transporters
ABCA1, ABCG1, APOA1, APOE, CETP, STARD3
Cholesterol Efflux
ABCA1, ABCG1, APOA1, APOA4, APOC3, APOE
Reverse Cholesterol Transport
ABCA1, APOA1, APOA2, APOA4, APOC3, APOE, CETP, LCAT
Other Cholesterol Transport Genes
APOB, LDLR, NPC1L1, OSBPL5
Cholesterol Metabolism
Cholesterol Absorption
CEL, LDLR, NPC1L1
Cholesterol Catabolism
AKR1D1, APOE, CEL, CYP39A1, CYP46A1, CYP7A1, SCARF1, SNX17, TRERF1
Cholesterol Homeostasis
ABCA1, ABCG1, ANGPTL3, APOA1, APOA2, APOA4, APOC3, APOE, CETP, LCAT, LDLR, LDLRAP1, PCSK9
Cholesterol Biosynthesis
ACAA2, CNBP, CYB5R3, CYP51A1, DHCR24, DHCR7, FDFT1, FDPS, HMGCR, HMGCS1, HMGCS2, IDI1, IDI2, MVD, MVK, NPC1L1, NSDHL, PMVK, PRKAA1 (AMPK), PRKAA2, PRKAG2, TM7SF2
Other Cholesterol Metabolism Genes
APOB, APOF, APOL1, APOL2, CYP11A1, CYP7B1, CELA3A, CELA3B, HDLBP, IL4, INSIG1, INSIG2, LEP (Leptin), LIPE, MBTPS1, NR0B2, NR1H4, OSBPL1A, OSBPL5, PPARD, SCAP, SOAT1, SORL1, SREBF1, SREBF2, STARD3, VLDLR