Gliomas are one of the most common central nervous system tumors, arising from astrocytes, oligodendrocytes or their precursors. These tumors are graded from I to IV with stage IV or Glioblastoma multiformes (GBM) being the most aggressive of the gliomas. GBMs can form by a de novo pathway to give rise to primary GBMs. Alternatively, through the acquisition of additional mutations, there can be progression from lower grades of glioma to GBM via secondary pathways. (secondary GBM)...