miRNA Localization Studies

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Detect any miRNA with high specificity and sensitivity

Our collection of predesigned miRCURY LNA miRNA Detection Probes covers most known invertebrate, vertebrate and plant miRNAs that are annotated in miRbase, and we offer the possibility to create your own custom probes for analysis of novel targets. The probes are designed with optimal LNA positioning for high sequence specificity, low secondary structure and minimal self-annealing.

The resulting superior binding affinity lets you specifically and sensitively detect any miRNA with an exceptionally high signal-to-noise ratio via in situ hybridization (ISH) and Northern blotting experiments. The probes can be used for a large number of applications, including cellular and sub-cellular miRNA localization studies and determination of spatial miRNA expression. The robustness of the procedure makes them a great tool for use in both high-throughput ISH analysis and localization studies of individual miRNAs.

Related Applications and Insights

LNA technology center
LNA technology center
Discover how the high affinity of locked nucleic acids (LNA) to their targets helps overcome the difficulties of studying very short DNA and RNA fragments
Learn more
Detection/ISH custom builders
Detection/ISH custom builders
Create high-performance mRNA/lncRNA and miRNA detection probes for your ISH, Northern blotting or localization studies
Learn more

Products (2)

Product Type
miRNA Detection Probes
miRCURY LNA miRNA Detection ProbesmiRCURY LNA miRNA Detection Probes

For ultra-sensitive and specific miRNA detection by in situ hybridization (ISH) or Northern blotting

miRCURY LNA miRNA Custom Detection ProbesmiRCURY LNA miRNA Custom Detection Probes

For ultra-sensitive and specific detection of novel miRNA sequences by in situ hybridization (ISH) or Northern blotting