mRNA/lncRNA Localization Studies

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Specifically and sensitively detect any RNA target

Our Custom LNA mRNA Detection Probes are designed with optimal LNA positioning to achieve high sequence specificity, low secondary structure and minimal self-annealing. This gives you superior binding affinity and very specific and sensitive detection, with an exceptionally high signal-to-noise ratio. Our user-friendly online design tool lets you easily design highly sensitive LNA probes for your specific mRNA sequence of interest.

The probes are great for in situ hybridization and cell or tissue imaging applications requiring a short probe, such as in the detection of short sequence mutations or for discriminating between closely related sequences such as splice variants and isoforms. And their high affinity for their target sequences allows use of stringent hybridization and washing conditions, despite the short probe lengths.

Related Applications and Insights

LNA technology center
LNA technology center
Discover how the high affinity of locked nucleic acids (LNA) to their targets helps overcome the difficulties of studying very short DNA and RNA fragments
Learn more
Detection/ISH custom builders
Detection/ISH custom builders
Create high-performance mRNA/lncRNA and miRNA detection probes for your ISH, Northern blotting or localization studies
Learn more

Products (1)

Product Type
mRNA Detection Probes
Custom LNA mRNA Detection ProbesCustom LNA mRNA Detection Probes

For ultra-sensitive detection of mRNA and lncRNA by in situ hybridization and Northern blotting