Digital PCR Assays for DNA Targets

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High sensitivity, superior precision and absolute quantification

Digital PCR is an excellent tool for detecting low abundance targets, rare allelic variants, small fold-change differences and targets in complex mixtures. Plus, its accuracy is less sensitive to changes in amplification efficiency or the presence of inhibitors.

Our collection of expertly designed dPCR assays supports analysis of DNA targets for a variety of applications. For CNV analysis, you can easily detect subtle fold changes in copy number, without a standard curve. For detection of somatic mutations or other genetic variants, you can quantify low-abundance mutations in a background of wild-type genomic DNA. Or, for microbial detection and monitoring, you can quantify a wide range of microbial targets – including bacterial, fungal, parasitic, viral, antibiotic resistance and virulence factor genes – from diverse samples.

Related Applications and Insights

Detect the smallest changes with the highest precision
Detect the smallest changes with the highest precision
Our validated assays for the QIAcuity Digital PCR System enable highly precise mutation detection, copy number variation analysis and gene expression analysis
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Webinar: analyze copy number variation by dPCR
Webinar: analyze copy number variation by dPCR
See how quantitative analysis of CNVs provides insights into molecular mechanisms of diseases and offers potential for novel biomarker discovery
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Webinar: LNA-enhanced dPCR mutation detection
Webinar: LNA-enhanced dPCR mutation detection
See how to reliably detect genetic alterations in oncogenes in precious samples such as ccfDNA from blood and other body fluids
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Webinar: dPCR-based pathogen detection
Webinar: dPCR-based pathogen detection
See how dPCR enables rapid profiling and identification of microbial species, antibiotic resistance genes and virulence genes from diverse samples
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Products (4)

Species
Analyte
Product Type
Copy Number Analysis
dPCR CNV Probe AssaysdPCR CNV Probe Assays

For locus-specific analysis of copy number variations and alterations by singleplex or multiplex dPCR

dPCR Copy Number AssaysdPCR Copy Number Assays

For locus-specific analysis of copy number variations and alterations

Somatic Mutation Detection
dPCR LNA Mutation AssaysdPCR LNA Mutation Assays

For detecting specific DNA sequence mutations related to cancer and oncogenesis

Microbial DNA dPCR
dPCR Microbial DNA Detection AssaysdPCR Microbial DNA Detection Assays

For digital PCR detection of microbial targets, including bacterial, fungal, parasitic, viral, antibiotic resistance or virulence factor genes