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p53 Signaling

The p53 (TP53) tumor suppressor protein is a key transcriptional regulator that responds to a variety of cellular stresses such as DNA damage, UV irradiation, and hypoxia. p53 regulates key cellular processes such as DNA repair, cell-cycle progression, angiogenesis, and apoptosis. These p53-dependent pathways shut down damaged cells, either through apoptosis or cell-cycle arrest. Loss of p53 function is thought to be a contributing factor in the majority of cancer cases....

p53 Signaling

Pathway Summary

The p53 (TP53) tumor suppressor protein is a key transcriptional regulator that responds to a variety of cellular stresses such as DNA damage, UV irradiation, and hypoxia. p53 regulates key cellular processes such as DNA repair, cell-cycle progression, angiogenesis, and apoptosis. These p53-dependent pathways shut down damaged cells, either through apoptosis or cell-cycle arrest. Loss of p53 function is thought to be a contributing factor in the majority of cancer cases.

p53 Signaling Genes list

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Products related to p53 Signaling

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GeneGlobe ID: UPHS-050Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels
QuantiNova LNA Probe PCR Focus Panel Human Cellular Senescence
QuantiNova LNA Probe PCR Focus Panel
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GeneGlobe ID: UPHS-027Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels
QuantiNova LNA Probe PCR Focus Panel Human p53 Signaling Pathway
QuantiNova LNA Probe PCR Focus Panel
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GeneGlobe ID: SBHS-027Z | Cat. No.: 249950 | QuantiNova LNA PCR Focus Panels
QuantiNova LNA PCR Focus Panel Human p53 Signaling Pathway
QuantiNova LNA PCR Focus Panel
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GeneGlobe ID: SBHS-050Z | Cat. No.: 249950 | QuantiNova LNA PCR Focus Panels
QuantiNova LNA PCR Focus Panel Human Cellular Senescence
QuantiNova LNA PCR Focus Panel
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GeneGlobe ID: PAHS-027Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays
RT² Profiler™ PCR Array Human p53 Signaling Pathway
RT2 Profiler PCR Array
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GeneGlobe ID: PAHS-050Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays
RT² Profiler™ PCR Array Human Cellular Senescence
RT2 Profiler PCR Array
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